Interferon-induced transmembrane protein 3 (ifitm3) Recombinant Protein | Ifitm3 recombinant protein

Recombinant Rat Interferon-induced transmembrane protein 3 (ifitm3)

• Gene Names: Ifitm3; rat8; DSPA2b
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Interferon-induced transmembrane protein 3 (ifitm3); Recombinant Rat Interferon-induced transmembrane protein 3 (ifitm3); Recombinant Interferon-induced transmembrane protein 3 (ifitm3); Interferon-induced transmembrane protein 3; Ifitm3 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-137
• Sequence: MNHTSQAFVNAATGGQPPNYERIKEEYEVSELGAPHGSASVRTTVINMPREVSVPDHVVWSLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDMTGAQAYASTAKCLNISSLVLSILMVIITIVTVVIIALNAPRLQT
• Sequence Length: 137

• Species: Rattus norvegicus (Rat)
• Preparation and Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 209915621
• NCBI GeneID: 361673
• NCBI Accession #: NP_001129596.1
• NCBI GenBank Nucleotide #: NM_001136124.1
• UniProt Accession #: P26376; B5DER6; AAB22754
• Molecular Weight: 14,971 Da
• NCBI Official Full Name: interferon-induced transmembrane protein 3
• NCBI Official Synonym Full Names: interferon induced transmembrane protein 3
• NCBI Official Symbol: Ifitm3
• NCBI Official Synonym Symbols: rat8; DSPA2b
• NCBI Protein Information: interferon-induced transmembrane protein 3; dispanin subfamily A member 2b; interferon-inducible protein variant 10
• UniProt Protein Name: Interferon-induced transmembrane protein 3
• Protein Family: Interferon-induced transmembrane protein
• UniProt Gene Name: ifitm3
• UniProt Synonym Gene Names: DSPA2b
• UniProt Entry Name: IFM3_RAT

Uniprot Description

IFITM3: IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. Interacts with SPP1; the interaction reduces OPN expression. By IFN-alpha and IFNG/IFN-gamma. Belongs to the CD225/Dispanin family.

Protein type: Membrane protein, integral; Cell surface

Cellular Component: cell surface; late endosome membrane; lysosomal membrane; apical part of cell; endoplasmic reticulum; cytoplasmic membrane-bound vesicle; cytoplasm; plasma membrane; integral to membrane; nucleus

Biological Process: receptor-mediated endocytosis; negative regulation of cell proliferation; negative regulation of viral transcription; negative regulation of viral genome replication; negative regulation of virion penetration into host cell; response to virus; heart development; defense response to virus; cardiac muscle cell differentiation