Single-minded homolog 1 (SIM1) Recombinant Protein | SIM1 recombinant protein

Recombinant Human Single-minded homolog 1 (SIM1)

Cat. Num. AAA964310

• Gene Names: SIM1; bHLHe14
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Single-minded homolog 1 (SIM1); Recombinant Human Single-minded homolog 1 (SIM1); SIM1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-766, Full length protein
• Sequence: MKEKSKNAARTRREKENSEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRVVFPEGLGEAWGHSSRTSPLDNVGRELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIYEYIHPADHDEMTAVLTAHQPYHSHFVQEYEIERSFFLRMKCVLAKRNAGLTCGGYKVIHCSGYLKIRQYSLDMSPFDGCYQNVGLVAVGHSLPPSAVTEIKLHSNMFMFRASLDMKLIFLDSRVAELTGYEPQDLIEKTLYHHVHGCDTFHLRCAHHLLLVKGQVTTKYYRFLAKHGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDTEYKGLQLSLDQISASKPAFSYTSSSTPTMTDNRKGAKSRLSSSKSKSRTSPYPQYSGFHTERSESDHDSQWGGSPLTDTASPQLLDPADRPGSQHDASCAYRQFSDRSSLCYGFALDHSRLVEERHFHTQACEGGRCEAGRYFLGTPQAGREPWWGSRAALPLTKASPESREAYENSMPHIASVHRIHGRGHWDEDSVVSSPDPGSASESGDRYRTEQYQSSPHEPSKIETLIRATQQMIKEEENRLQLRKAPSDQLASINGAGKKHSLCFANYQQPPPTGEVCHGSALANTSPCDHIQQREGKMLSPHENDYDNSPTALSRISSPNSDRISKSSLILAKDYLHSDISPHQTAGDHPTVSPNCFGSHRQYFDKHAYTLTGYALEHLYDSETIRNYSLGCNGSHFDVTSHLRMQPDPAQGHKGTSVIITNGS
• Sequence Length: 766

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for SIM1 recombinant protein

SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and
or mental retardation of Down syndrome.

NCBI and Uniprot Product Information

• NCBI GI #: 21614542
• NCBI GeneID: 6492
• NCBI Accession #: NP_005059.2
• NCBI GenBank Nucleotide #: NM_005068.2
• UniProt Accession #: P81133; Q5TDP7
• Molecular Weight: 85,515 Da
• NCBI Official Full Name: single-minded homolog 1
• NCBI Official Synonym Full Names: single-minded family bHLH transcription factor 1
• NCBI Official Symbol: SIM1
• NCBI Official Synonym Symbols: bHLHe14
• NCBI Protein Information: single-minded homolog 1
• UniProt Protein Name: Single-minded homolog 1
• Protein Family: Single-minded
• UniProt Gene Name: SIM1
• UniProt Synonym Gene Names: BHLHE14; bHLHe14

NCBI Description

SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or cognitive disability of Down syndrome. [provided by RefSeq, Jul 2008]

Uniprot Description

Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult.