POMK blocking peptide
POMK Antibody
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Uniprot Description
POMK: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.
Protein type: EC 2.7.1.183; Protein kinase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; Protein kinase, Other; Membrane protein, integral; Kinase, protein; Other group; Other-Unique family
Chromosomal Location of Human Ortholog: 8p11.21
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: ATP binding; carbohydrate kinase activity; phosphotransferase activity, alcohol group as acceptor; protein kinase activity
Biological Process: brain development; carbohydrate phosphorylation; learning and/or memory; neuromuscular process; neuron migration; protein amino acid O-linked glycosylation; protein amino acid phosphorylation; sensory perception of pain
Disease: Muscular Dystrophy-dystroglycanopathy (congenital With Brain And Eye Anomalies), Type A, 12; Muscular Dystrophy-dystroglycanopathy (limb-girdle), Type C, 12
Research Articles on POMK
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Product Notes
The POMK pomk (Catalog #AAA9633508) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "POMK, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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