Rabbit EML1 Polyclonal Antibody | anti-EML1 antibody
EML1 Antibody
Gene Names
EML1; EMAP; ELP79; EMAPL; HuEMAP
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
EML1; Polyclonal Antibody; EML1 Antibody; echinoderm microtubule associated protein like 1; Echinoderm microtubule-associated protein-like 1; ELP79; EMAL1_HUMAN; EMAP; EMAP-1; EMAPL; Eml1; FLJ45033; HuEMAP; HuEMAP-1; anti-EML1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
EML1 Antibody detects endogenous levels of EML1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-EML1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human EML1.
Conjugation
Unconjugated
Similarity
Contains a tandem atypical propeller in EMLs (TAPE) domain. The N-terminal beta-propeller is formed by canonical WD repeats; in contrast, the second beta-propeller contains one blade that is formed by discontinuous parts of the polypeptide chain. Belongs to the WD repeat EMAP family.
Subunit Structure
Binds repolymerizing microtubules. Binds unpolymerized tubulins via its WD repeat region.
Tissue Specificity
Ubiquitous; expressed in most tissues with the exception of thymus and peripheral blood lymphocytes.
Function
Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se.
Note
Detected in cytoplasmic punctae. Co-localizes with microtubules (PubMed:24859200). Enriched in perinuclear regions during interphase and in the region of spindle microtubules during metaphase. Enriched at the midzone during telophase and cytokinesis. Detected at growth cones in neurons (By similarity).
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-EML1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
91,985 Da
NCBI Official Full Name
echinoderm microtubule-associated protein-like 1 isoform b
NCBI Official Synonym Full Names
echinoderm microtubule associated protein like 1
NCBI Official Symbol
EML1
NCBI Official Synonym Symbols
EMAP; ELP79; EMAPL; HuEMAP
NCBI Protein Information
echinoderm microtubule-associated protein-like 1; EMAP-1; huEMAP-1
UniProt Protein Name
Echinoderm microtubule-associated protein-like 1
Protein Family
UniProt Gene Name
EML1
UniProt Synonym Gene Names
EMAP1; EMAPL; EMAPL1; EMAP-1; HuEMAP-1
UniProt Entry Name
EMAL1_HUMAN
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Product Notes
The EML1 eml1 (Catalog #AAA9630611) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EML1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EML1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the EML1 eml1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EML1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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