Rabbit anti-Human, Mouse DENND5A Polyclonal Antibody | anti-DENND5A antibody
DENND5A Antibody
Gene Names
DENND5A; RAB6IP1
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
DENND5A; Polyclonal Antibody; DENND5A Antibody; DEN5A_HUMAN; DENN domain-containing protein 5A; DENN/MADD domain containing 5A; Dennd5a; FLJ22354; FLJ33829; FLJ43455; ; KIAA1091; RAB6 interacting protein 1; Rab6-interacting protein 1; Rab6IP1; anti-DENND5A antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
DENND5A Antibody detects endogenous levels of DENND5A.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-DENND5A antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human DENND5A.
Conjugation
Unconjugated
Similarity
Belongs to the RAB6IP1 family.
Subunit Structure
Interacts with RAB6A bound to GTP.
Function
Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth (By similarity).
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-DENND5A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
141,982 Da
NCBI Official Full Name
DENN domain-containing protein 5A isoform 2
NCBI Official Synonym Full Names
DENN/MADD domain containing 5A
NCBI Official Symbol
DENND5A
NCBI Official Synonym Symbols
RAB6IP1
NCBI Protein Information
DENN domain-containing protein 5A
UniProt Protein Name
DENN domain-containing protein 5A
Protein Family
UniProt Gene Name
DENND5A
UniProt Synonym Gene Names
KIAA1091; RAB6IP1; Rab6IP1
UniProt Entry Name
DEN5A_HUMAN
Uniprot Description
RAB6IP1: a Golgi-associated guanine nucleotide exchange factor (GEF) that activates RAB6A and RAB39A/B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Interacts with RAB6A bound to GTP. Belongs to the RAB6IP1 family.
Protein type: GEFs, Rab; GEFs
Chromosomal Location of Human Ortholog: 11p15.4
Cellular Component: membrane; retromer complex; trans-Golgi network
Molecular Function: calcium channel activity; Rab guanyl-nucleotide exchange factor activity; Rab GTPase binding
Biological Process: detection of mechanical stimulus; retrograde transport, endosome to Golgi
Research Articles on DENND5A
Similar Products
Product Notes
The DENND5A dennd5a (Catalog #AAA9630286) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DENND5A Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DENND5A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the DENND5A dennd5a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DENND5A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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