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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human rectum tissue using MBS7005715 at dilution of 1:100)

Rabbit anti-Human DENND5A Polyclonal Antibody | anti-DENND5A antibody

DENND5A Antibody

Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%,Protein G purified
Synonyms
DENND5A; Polyclonal Antibody; DENND5A Antibody; DENN domain-containing protein 5A; Rab6-interacting protein 1; Rab6IP1; KIAA1091; RAB6IP1; anti-DENND5A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Sequence Length
1241
Applicable Applications for anti-DENND5A antibody
ELISA (EIA), Immunohistochemistry (IHC)
Immunogen
Recombinant human DENN domain-containing protein 5A protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human rectum tissue using MBS7005715 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human rectum tissue using MBS7005715 at dilution of 1:100)
Related Product Information for anti-DENND5A antibody
Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
141,982 Da
NCBI Official Full Name
DENN domain-containing protein 5A isoform 2
UniProt Protein Name
DENN domain-containing protein 5A
UniProt Gene Name
DENND5A
UniProt Synonym Gene Names
KIAA1091; RAB6IP1; Rab6IP1
UniProt Entry Name
DEN5A_HUMAN

Uniprot Description

RAB6IP1: a Golgi-associated guanine nucleotide exchange factor (GEF) that activates RAB6A and RAB39A/B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Interacts with RAB6A bound to GTP. Belongs to the RAB6IP1 family.

Protein type: GEFs, Rab; GEFs

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: retromer complex; trans-Golgi network

Molecular Function: calcium channel activity; Rab GTPase binding; Rab guanyl-nucleotide exchange factor activity

Biological Process: detection of mechanical stimulus; positive regulation of GTPase activity; retrograde transport, endosome to Golgi

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Product Notes

The DENND5A dennd5a (Catalog #AAA7005715) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DENND5A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DENND5A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the DENND5A dennd5a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DENND5A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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