Rabbit anti-Human PVRIG Polyclonal Antibody | anti-PVRIG antibody
PVRIG Antibody
Gene Names
PVRIG; C7orf15
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
PVRIG; Polyclonal Antibody; PVRIG Antibody; Poliovirus receptor-related immunoglobulin domain-containing protein; PVRIG_HUMAN; Transmembrane protein PVRIG; anti-PVRIG antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
PVRIG Antibody detects endogenous levels of PVRIG.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-PVRIG antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human PVRIG.
Conjugation
Unconjugated
Subunit Structure
Interacts with NECTIN2, hence competing with CD226.
Tissue Specificity
Expressed in some types of immune cells. Expressed at low levels on the surface of freshly isolated T-cells and natural killer (NK) cells, predominantly on CD8+ T-cells (mainly memory/effector, but not naive cells) and on both CD16+ and CD16- NK cells. T-cell expression levels are variable among individuals. Not detected in B-cells, naive or helper T-cells, monocytes, nor neutrophils (at protein level). Not detected in dendritic cells.
Function
Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-PVRIG antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,344 Da
NCBI Official Full Name
transmembrane protein PVRIG
NCBI Official Synonym Full Names
poliovirus receptor related immunoglobulin domain containing
NCBI Official Symbol
PVRIG
NCBI Official Synonym Symbols
C7orf15
NCBI Protein Information
transmembrane protein PVRIG; poliovirus receptor-related immunoglobulin domain-containing protein
UniProt Protein Name
Transmembrane protein PVRIG
Protein Family
UniProt Gene Name
PVRIG
UniProt Synonym Gene Names
C7orf15
UniProt Entry Name
PVRIG_HUMAN
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Product Notes
The PVRIG pvrig (Catalog #AAA9630250) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PVRIG Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PVRIG can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the PVRIG pvrig for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PVRIG, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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