Rabbit anti-Human, Mouse EXT2 Polyclonal Antibody | anti-EXT2 antibody
EXT2 Antibody
Gene Names
EXT2; SOTV
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
EXT2; Polyclonal Antibody; EXT2 Antibody; Exostoses (multiple) 2; Exostosin 2; Exostosin-2; EXT2_HUMAN; Glucuronosyl N acetylglucosaminyl proteoglycan 4 alpha N acetylglucosaminyltransferase; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Multiple exostoses protein 2; N acetylglucosaminyl proteoglycan 4 beta glucuronosyltransferase; Putative tumor suppressor protein EXT2; SOTV; anti-EXT2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
EXT2 Antibody detects endogenous levels of EXT2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-EXT2 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human EXT2.
Conjugation
Unconjugated
Similarity
Belongs to the glycosyltransferase 47 family.
Subunit Structure
Forms a homo/hetero-oligomeric complex with EXT1. Interacts with GALNT5. Interacts with NDST1.
Tissue Specificity
Ubiquitous.
Function
Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan.
Note
The EXT1/EXT2 complex is localized in the Golgi apparatus.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-EXT2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
85,815 Da
NCBI Official Full Name
exostosin-2 isoform 1
NCBI Official Synonym Full Names
exostosin glycosyltransferase 2
NCBI Official Symbol
EXT2
NCBI Official Synonym Symbols
SOTV
NCBI Protein Information
exostosin-2; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase; glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; multiple exostoses protein 2; putative tumor suppresso
UniProt Protein Name
Exostosin-2
Protein Family
UniProt Gene Name
EXT2
UniProt Entry Name
EXT2_HUMAN
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Product Notes
The EXT2 ext2 (Catalog #AAA9630203) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EXT2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's EXT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the EXT2 ext2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EXT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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