TGIF1 blocking peptide

TGIF1 Blocking Peptide

Cat. Num. AAA9626983

• Gene Names: TGIF1; HPE4; TGIF
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: TGIF1; TGIF1 Blocking Peptide; 5' TG 3' interacting factor; 5''-TG-3''-interacting factor 1; Homeobox protein TGIF; Homeobox protein TGIF1; HPE4; MGC39747; MGC5066; TALE homeobox TG-interacting factor; TG interacting factor isoform c; TG-interacting factor; TGFB induced factor; TGFB-induced factor homeobox 1; TGIF1_HUMAN; transforming growth factor-beta-induced factor; TGIF1 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for TGIF1 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for TGIF1 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 522838237
• NCBI GeneID: 7050
• NCBI Accession #: NP_001265611.1
• NCBI GenBank Nucleotide #: NM_001278682.1
• UniProt Accession #: Q15583; Q6ICR0; Q8N5X9; Q9NRS0; A6NE42; A6NLU7; F8VZB6
• Molecular Weight: 27,715 Da
• NCBI Official Full Name: homeobox protein TGIF1 isoform e
• NCBI Official Synonym Full Names: TGFB induced factor homeobox 1
• NCBI Official Symbol: TGIF1
• NCBI Official Synonym Symbols: HPE4; TGIF
• NCBI Protein Information: homeobox protein TGIF1
• UniProt Protein Name: Homeobox protein TGIF1
• Protein Family: Homeobox protein
• UniProt Gene Name: TGIF1
• UniProt Synonym Gene Names: TGIF
• UniProt Entry Name: TGIF1_HUMAN

NCBI Description

The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2013]