MRIP blocking peptide
MRIP Blocking Peptide
Gene Names
MPRIP; MRIP; RIP3; M-RIP; RHOIP3; p116Rip
Applications
Blocking/Control
Purity
The purity is >90%,tested by HPLC and MS.
Synonyms
MRIP; MRIP Blocking Peptide; 9530046C02; AA536749; AI647711; C76423; KIAA0864; M-RIP; MGC67316; mKIAA0864; Mprip; MPRIP_HUMAN; Myosin phosphatase Rho-interacting protein; p116 Rho-interacting protein; p116Rip; Rho-interacting protein 3; Rhoip3; RIP3; RP23-180B18.4; MRIP blocking peptide
Purity/Purification
The purity is >90%,tested by HPLC and MS.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.
Applicable Applications for MRIP blocking peptide
Blocking/Control
Notes
For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for MRIP blocking peptide
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
116,533 Da
NCBI Official Full Name
myosin phosphatase Rho-interacting protein isoform 1
NCBI Official Synonym Full Names
myosin phosphatase Rho interacting protein
NCBI Official Symbol
MPRIP
NCBI Official Synonym Symbols
MRIP; RIP3; M-RIP; RHOIP3; p116Rip
NCBI Protein Information
myosin phosphatase Rho-interacting protein; Rho interacting protein 3
UniProt Protein Name
Myosin phosphatase Rho-interacting protein
UniProt Gene Name
MPRIP
UniProt Synonym Gene Names
KIAA0864; MRIP; RHOIP3; M-RIP; RIP3
UniProt Entry Name
MPRIP_HUMAN
Uniprot Description
RIP3: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F- actin-binding region leads to disassembly of stress fibers in neuronal cells. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs, Rac/Rho; GAPs
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component: focal adhesion; cytoplasm; actin cytoskeleton
Molecular Function: protein binding; actin binding
Research Articles on MRIP
Similar Products
Product Notes
The MRIP mprip (Catalog #AAA9624937) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MRIP can be used in a range of immunoassay formats including, but not limited to, Blocking/Control. Researchers should empirically determine the suitability of the MRIP mprip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRIP, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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