SRP68 blocking peptide

SRP68 Blocking Peptide

Cat. Num. AAA9620937

• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: SRP68; SRP68 Blocking Peptide; Signal recognition particle 68; Signal recognition particle 68 kDa; Signal recognition particle 68 kDa protein; signal recognition particle 68kD; Signal recognition particle 68kDa; signal recognition particle subunit SRP68; SRP 68; SRP68_HUMAN; SRP68 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for SRP68 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for SRP68 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 386781688
• NCBI GeneID: 6730
• NCBI Accession #: NP_001247431.1
• NCBI GenBank Nucleotide #: NM_001260502.1
• UniProt Accession #: Q9UHB9; Q8NCJ4; Q8WUK2; B3KUU5; B3KWY7; G3V1U4
• Molecular Weight: 70,730 Da
• NCBI Official Full Name: signal recognition particle subunit SRP68 isoform 2
• NCBI Official Synonym Full Names: signal recognition particle 68kDa
• NCBI Official Symbol: SRP68
• NCBI Protein Information: signal recognition particle subunit SRP68; signal recognition particle 68kD; signal recognition particle 68 kDa protein
• UniProt Protein Name: Signal recognition particle subunit SRP68
• Protein Family: Signal recognition particle
• UniProt Gene Name: SRP68
• UniProt Synonym Gene Names: SRP68
• UniProt Entry Name: SRP68_HUMAN

Uniprot Description

SRP68: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. Belongs to the SRP68 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Endoplasmic reticulum; Nucleolus; RNA-binding

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: focal adhesion; endoplasmic reticulum; cytoplasm; nucleolus; signal recognition particle, endoplasmic reticulum targeting; ribosome; cytosol

Molecular Function: signal recognition particle binding; signal sequence binding; endoplasmic reticulum signal peptide binding; 7S RNA binding

Biological Process: response to drug; protein targeting to ER; SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translation; gene expression