Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using SRP68 Polyclonal Antibody at dilution 1:25)
Rabbit SRP68 Polyclonal Antibody | anti-SRP68 antibody
SRP68 Polyclonal Antibody
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using SRP68 Polyclonal Antibody at dilution 1:25)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using SRP68 Polyclonal Antibody at dilution 1:25)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a subunit of the signal recognition particle (SRP). The SRP is a ribonucleoprotein complex that transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA and six protein subunits. The encoded protein is the 68kDa component of the SRP, and forms a heterodimer with the 72kDa subunit that is required for SRP function. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and three pseudogenes of this gene are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, May 2012]
Uniprot Description
SRP68: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. Belongs to the SRP68 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleolus; Endoplasmic reticulum; RNA-binding
Chromosomal Location of Human Ortholog: 17q25.1
Cellular Component: focal adhesion; endoplasmic reticulum; cytoplasm; signal recognition particle, endoplasmic reticulum targeting; nucleolus; ribosome; cytosol
Molecular Function: signal recognition particle binding; signal sequence binding; endoplasmic reticulum signal peptide binding; 7S RNA binding
Biological Process: response to drug; SRP-dependent cotranslational protein targeting to membrane; protein targeting to ER; cellular protein metabolic process; translation; gene expression
Research Articles on SRP68
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Product Notes
The SRP68 srp68 (Catalog #AAA2525763) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SRP68 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SRP68 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:25-1:100. Researchers should empirically determine the suitability of the SRP68 srp68 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRP68, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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