VPS33B blocking peptide

VPS33B Blocking Peptide

Cat. Num. AAA9620886

• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: VPS33B; VPS33B Blocking Peptide; FLJ14848; hVPS 33B; hVPS33B; Vacuolar protein sorting 33 homolog B (yeast); Vacuolar protein sorting 33 homolog B; Vacuolar protein sorting 33B (yeast); Vacuolar protein sorting 33B; Vacuolar protein sorting associated protein 33B; VPS 33B; VPS33B blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for VPS33B blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for VPS33B blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 574584823
• NCBI GeneID: 26276
• NCBI Accession #: NP_001276077.1
• NCBI GenBank Nucleotide #: NM_001289148.1
• UniProt Accession #: Q9H267; Q96K14; Q9NRP6; Q9NSF3; B3KQF6
• Molecular Weight: 60,032 Da
• NCBI Official Full Name: vacuolar protein sorting-associated protein 33B isoform 2
• NCBI Official Synonym Full Names: VPS33B, late endosome and lysosome associated
• NCBI Official Symbol: VPS33B
• NCBI Protein Information: vacuolar protein sorting-associated protein 33B
• UniProt Protein Name: Vacuolar protein sorting-associated protein 33B
• Protein Family: Vacuolar protein sorting-associated protein
• UniProt Gene Name: VPS33B
• UniProt Synonym Gene Names: hVPS33B
• UniProt Entry Name: VP33B_HUMAN

NCBI Description

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]