Western Blot (WB)
(Western blot analysis of extracts from K562, using HBZ Antibody. The lane on the left was treated with blocking peptide.)
Rabbit HBZ Polyclonal Antibody | anti-HBZ antibody
HBZ Antibody
Predicted Reactivity: Pig(100%), Bovine(100%)
Predicted Reactivity: Pig(100%), Bovine(100%)
ELISA(peptide): 1:20,000-1:40,000
Western Blot (WB)
(Western blot analysis of extracts from K562, using HBZ Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from K562, using HBZ Antibody. The lane on the left was treated with blocking peptide.)
Tissue Specificity: Detected in fetal erythrocytes (at protein level).
Subunit Structure: Heterotetramer of two zeta chains and two epsilon chains in early embryonic hemoglobin Gower-1; two zeta chains and two gamma chains in fetal hemoglobin Portland-1. Heterotetramer of two zeta chains and two beta chains in hemoglobin Portland-2, detected in fetuses and neonates with homozygous alpha-thalassemia.
Similarity: Belongs to the globin family.
NCBI and Uniprot Product Information
Predicted Molecular Weight: (Calculated)16kDa.
NCBI Description
Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'. [provided by RefSeq, Nov 2009]
Uniprot Description
HBZ: The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin, synthesized primarily in the yolk sac. Belongs to the globin family.
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: hemoglobin complex
Molecular Function: protein binding; iron ion binding; heme binding; oxygen binding; oxygen transporter activity
Biological Process: erythrocyte maturation; oxygen transport; negative regulation of transcription from RNA polymerase II promoter
Research Articles on HBZ
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Product Notes
The HBZ hbz (Catalog #AAA9612159) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HBZ Antibody reacts with Human Predicted Reactivity: Pig(100%), Bovine(100%) and may cross-react with other species as described in the data sheet. AAA Biotech's HBZ can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). WB: 1:500-1:2000 ELISA(peptide): 1:20,000-1:40,000. Researchers should empirically determine the suitability of the HBZ hbz for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HBZ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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