Small conductance calcium-activated potassium channel protein 2 (Kcnn2) Recombinant Protein | Kcnn2 recombinant protein
Recombinant Rat Small conductance calcium-activated potassium channel protein 2 (Kcnn2)
NCBI and Uniprot Product Information
NCBI Description
small-conductance, calcium-activated potassium channel [RGD, Feb 2006]
Uniprot Description
KCNN2: Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. Belongs to the potassium channel KCNN family. KCa2.2/KCNN2 subfamily.
Protein type: Channel, potassium; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: smooth endoplasmic reticulum; cell soma; T-tubule; dendritic spine; integral to membrane; plasma membrane; Z disc
Molecular Function: calmodulin binding; calcium-activated potassium channel activity; protein binding; protein homodimerization activity; ion channel activity; alpha-actinin binding; small conductance calcium-activated potassium channel activity
Biological Process: ion transport; potassium ion transport; regulation of neuronal synaptic plasticity
Research Articles on Kcnn2
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Product Notes
The Kcnn2 kcnn2 (Catalog #AAA961080) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-580. The amino acid sequence is listed below: MSSCRYNGGV MRPLSNLSSS RRNLHEMDSE AQPLQPPASV VGGGGGASSP SAAAAASSSA PEIVVSKPEH NNSNNLALYG TGGGGSTGGG GGGGGGGGGS GHGSSSGTKS SKKKNQNIGY KLGHRRALFE KRKRLSDYAL IFGMFGIVVM VIETELSWGA YDKASLYSLA LKCLISLSTI ILLGLIIVYH AREIQLFMVD NGADDWRIAM TYERIFFICL EILVCAIHPI PGNYTFTWTA RLAFSYAPST TTADVDIILS IPMFLRLYLI ARVMLLHSKL FTDASSRSIG ALNKINFNTR FVMKTLMTIC PGTVLLVFSI SLWIIAAWTV RACERYHDQQ DVTSNFLGAM WLISITFLSI GYGDMVPNTY CGKGVCLLTG IMGAGCTALV VAVVARKLEL TKAEKHVHNF MMDTQLTKRV KNAAANVLRE TWLIYKNTKL VKKIDHAKVR KHQRKFLQAI HQLRSVKMEQ RKLNDQANTL VDLAKTQNIM YDMISDLNER SEDFEKRIVT LETKLETLIG SIHALPGLIS QTIRQQQRDF IETQMENYDK HVTYNAERSR SSSRRRRSSS TAPPTSSESS. It is sometimes possible for the material contained within the vial of "Small conductance calcium-activated potassium channel protein 2 (Kcnn2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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