Rabbit anti-Human MT-ATP6 Polyclonal Antibody | anti-MT-ATP6 antibody

MT-ATP6 Antibody

Cat. Num. AAA9609554

• Gene Names: MT-ATP6; ATPase6; MTATP6; ATP6
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Synonyms: MT-ATP6; Polyclonal Antibody; MT-ATP6 Antibody; ATP synthase subunit a; ATP6; ATP6_HUMAN; ATPASE6; F-ATPase protein 6; MTATP6; anti-MT-ATP6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: MT-ATP6 antibody detects endogenous levels of total MT-ATP6
• Purity/Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Form/Format: Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)
• Sequence Length: 226

• Applicable Applications for anti-MT-ATP6 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:1000-3000
• Immunogen: A synthesized peptide derived from human MT-ATP6
• Subcellular Location: Mitochondrion Inner Membrane.
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of MT-ATP6 using LOVO whole cell lysates)

Related Product Information for anti-MT-ATP6 antibody

Function: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1-containing the extramembraneous catalytic core and F0-containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
Subunit Structure: F-type ATPases have 2 components, CF1-the catalytic core-and CF0-the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c. Component of an ATP synthase complex composed of ATP5F1, ATP5MC1, ATP5F1E, ATP5H, ATP5I, ATP5J, ATP5J2, MT-ATP6, MT-ATP8, ATP5F1A, ATP5F1B, ATP5F1D, ATP5F1C, ATP5O, ATP5L, USMG5 and MP68 (By similarity).
Similarity: Belongs to the ATPase A chain family.

NCBI and Uniprot Product Information

• NCBI GI #: 251831112
• NCBI GeneID: 4508
• NCBI Accession #: YP_003024031.1
• NCBI GenBank Nucleotide #: NC_012920.1
• UniProt Accession #: P00846; Q34772; Q5S8W5; Q5S9E7; Q5S9I6; Q5SA31; Q6RPB7; Q6VHC0; Q6VHE0; Q6WQF4; Q7YCC1; Q7YCF8
• Molecular Weight: Observed: 25 kDa; Predicted: 25 kDa
• NCBI Official Full Name: ATP synthase F0 subunit 6 (mitochondrion)
• NCBI Official Synonym Full Names: mitochondrially encoded ATP synthase 6
• NCBI Official Symbol: MT-ATP6
• NCBI Official Synonym Symbols: ATPase6; MTATP6; ATP6
• NCBI Protein Information: ATP synthase F0 subunit 6
• UniProt Protein Name: ATP synthase subunit a
• UniProt Gene Name: MT-ATP6
• UniProt Synonym Gene Names: ATP6; ATPASE6; MTATP6

Uniprot Description

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.