Western Blot (WB)
(Western blot analysis SYT2 using K562 whole cell lysates)
Rabbit SYT2 Polyclonal Antibody | anti-SYT2 antibody
SYT2 Antibody
Gene Names
SYT2; CMS7; MYSPC; SytII
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
SYT2; Polyclonal Antibody; SYT2 Antibody; Synaptotagmin 2; Synaptotagmin II; Synaptotagmin-2; Synaptotagmin2; SynaptotagminII; SYT 2; Syt II; Syt2; SYT2_HUMAN; SytII; anti-SYT2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
SYT2 antibody detects endogenous levels of total SYT2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
419
Applicable Applications for anti-SYT2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human SYT2
Tissue Specificity
Expressed in melanocytes (PubMed:23999003).
Predicted Cross Reactivity
Pig, Bovine, Horse, Rabbit, Chicken
Similarity
Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Chicken (91%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis SYT2 using K562 whole cell lysates)
Western Blot (WB)
(Western blot analysis SYT2 using K562 whole cell lysates)
Related Product Information for anti-SYT2 antibody
Function: Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity). Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Subunit Structure: Homotetramer (Probable). Interacts with STON2 (PubMed:11381094). Interacts with SCAMP5 (PubMed:19234194). Interacts with PRRT2 (By similarity).
Similarity: The first C2 domain mediates Ca2+-dependent phospholipid binding.The second C2 domain mediates interaction with Stonin 2. The second C2 domain mediates phospholipid and inositol polyphosphate binding in a calcium-independent manner. Belongs to the synaptotagmin family.
Subunit Structure: Homotetramer (Probable). Interacts with STON2 (PubMed:11381094). Interacts with SCAMP5 (PubMed:19234194). Interacts with PRRT2 (By similarity).
Similarity: The first C2 domain mediates Ca2+-dependent phospholipid binding.The second C2 domain mediates interaction with Stonin 2. The second C2 domain mediates phospholipid and inositol polyphosphate binding in a calcium-independent manner. Belongs to the synaptotagmin family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 47 kDa
Predicted: 47 kDa
Predicted: 47 kDa
NCBI Official Full Name
synaptotagmin-2
NCBI Official Synonym Full Names
synaptotagmin 2
NCBI Official Symbol
SYT2
NCBI Official Synonym Symbols
CMS7; MYSPC; SytII
NCBI Protein Information
synaptotagmin-2
UniProt Protein Name
Synaptotagmin-2
Protein Family
UniProt Gene Name
SYT2
UniProt Synonym Gene Names
SytIIBy similarityManual assertion inferred from sequence similarity toiUniProtKB:P29101Â (SYT2_RAT)
NCBI Description
This gene encodes a synaptic vesicle membrane protein. The encoded protein is thought to function as a calcium sensor in vesicular trafficking and exocytosis. Mutations in this gene are associated with myasthenic syndrome, presynaptic, congenital, with or without motor neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Uniprot Description
Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties (). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (). Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Research Articles on SYT2
Similar Products
Product Notes
The SYT2 syt2 (Catalog #AAA9609366) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYT2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SYT2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the SYT2 syt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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