Western Blot (WB)
(Western blot analysis of ABCG1 using HT29 whole lysates.)
Rabbit anti-Human ABCG1 Polyclonal Antibody | anti-ABCG1 antibody
ABCG1 Antibody
Gene Names
ABCG1; ABC8; WHITE1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
ABCG1; Polyclonal Antibody; ABCG1 Antibody; ABC transporter 8; ABC8; ABCG1_HUMAN; ATP-binding cassette sub family G member 1; ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; ATP-binding cassette; sub family G WHITE member 1; homolog of Drosophila white; MGC34313; White protein homolog; White protein homolog ATP binding cassette transporter 8; WHITE1; WHT1; anti-ABCG1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
ABCG1 antibody detects endogenous levels of total ABCG1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
678
Applicable Applications for anti-ABCG1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human ABCG1
Subcellular Location
Endoplasmic Reticulum Membrane. Golgi Apparatus Membrane. Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum (ER) and golgi membranes.
Tissue Specificity
Expressed in several tissues. Expressed in macrophages; expression is increased in macrophages from patients with Tangier disease.
Predicted Cross Reactivity
Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken
Similarity
Pig (100%), Zebrafish (83%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%), Chicken (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of ABCG1 using HT29 whole lysates.)
Western Blot (WB)
(Western blot analysis of ABCG1 using HT29 whole lysates.)
Related Product Information for anti-ABCG1 antibody
Function: Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.
Subunit Structure: May form heterodimers with several heterologous partners of the ABCG subfamily.
Post-translational Modifications: Palmitoylation at Cys-315 seems important for trafficking from the endoplasmic reticulum.
Similarity: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
Subunit Structure: May form heterodimers with several heterologous partners of the ABCG subfamily.
Post-translational Modifications: Palmitoylation at Cys-315 seems important for trafficking from the endoplasmic reticulum.
Similarity: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 110 kDa
Predicted: 76 kDa
Predicted: 76 kDa
NCBI Official Full Name
ATP-binding cassette sub-family G member 1 isoform 4
NCBI Official Synonym Full Names
ATP binding cassette subfamily G member 1
NCBI Official Symbol
ABCG1
NCBI Official Synonym Symbols
ABC8; WHITE1
NCBI Protein Information
ATP-binding cassette sub-family G member 1
UniProt Protein Name
ATP-binding cassette sub-family G member 1
Protein Family
UniProt Gene Name
ABCG1
UniProt Synonym Gene Names
ABC8; WHT1
NCBI Description
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.MiscellaneousA protein of the expected size has been detected by antibody binding and Western blot in at least one of the analyzed tissues or cells.
Research Articles on ABCG1
Similar Products
Product Notes
The ABCG1 abcg1 (Catalog #AAA9608275) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ABCG1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ABCG1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the ABCG1 abcg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ABCG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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