Western Blot (WB)
(Western blot analysis of AEBP1 expression in HEK293 cells, The lane on the left is treated with the antigen-specific peptide.)
Rabbit AEBP1 Polyclonal Antibody | anti-AEBP1 antibody
AEBP1 Antibody
Gene Names
AEBP1; ACLP
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
AEBP1; Polyclonal Antibody; AEBP1 Antibody; anti-AEBP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
AEBP1 antibody detects endogenous levels of total AEBP1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1158
Applicable Applications for anti-AEBP1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide
Subcellular Location
Extracellular Region or Secreted; Nucleus
Tissue Specificity
Expressed in osteoblast and visceral fat.
Predicted Cross Reactivity
Pig, Horse, Sheep, Rabbit, Dog, Xenopus
Similarity
Pig (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Xenopus (80%)
Conjugation
Unconjugated
Western Blot (WB)
(Western blot analysis of AEBP1 expression in HEK293 cells, The lane on the left is treated with the antigen-specific peptide.)
Western Blot (WB)
(Western blot analysis of AEBP1 expression in HEK293 cells, The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-AEBP1 antibody
Function: May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor.
Subunit Structure: Interacts with GNG5, NFKBIA, MAPK1, MAPK3 and PTEN. May interact with calmodulin. Binds to DNA in vitro.
Post-translational Modifications: Phosphorylated by MAPK1 in vitro.
Similarity: Belongs to the peptidase M14 family.
Subunit Structure: Interacts with GNG5, NFKBIA, MAPK1, MAPK3 and PTEN. May interact with calmodulin. Binds to DNA in vitro.
Post-translational Modifications: Phosphorylated by MAPK1 in vitro.
Similarity: Belongs to the peptidase M14 family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 131 kDa
NCBI Official Full Name
adipocyte enhancer-binding protein 1
NCBI Official Synonym Full Names
AE binding protein 1
NCBI Official Symbol
AEBP1
NCBI Official Synonym Symbols
ACLP
NCBI Protein Information
adipocyte enhancer-binding protein 1
UniProt Protein Name
Adipocyte enhancer-binding protein 1
Protein Family
UniProt Gene Name
AEBP1
UniProt Synonym Gene Names
ACLP; AE-binding protein 1
NCBI Description
This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma. [provided by RefSeq, May 2013]
Uniprot Description
Isoform 1: As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellualr matrix.
Research Articles on AEBP1
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Product Notes
The AEBP1 aebp1 (Catalog #AAA9603941) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AEBP1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AEBP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the AEBP1 aebp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AEBP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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