Western Blot (WB)
(Western blot analysis of LAMB3 expression in HEK293 cells, The lane on the left is treated with the antigen-specific peptide.)
Rabbit anti-Human, Mouse LAMB3 Polyclonal Antibody | anti-LAMB3 antibody
LAMB3 Antibody
Gene Names
LAMB3; AI1A; LAM5; LAMNB1; BM600-125KDA
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
LAMB3; Polyclonal Antibody; LAMB3 Antibody; BM600 125KDA; Epiligrin subunit bata; FLJ99565; Kalinin B1 chain; Kalinin subunit beta; LAM5; LAMB3_HUMAN; Laminin B1k chain; Laminin subunit beta-3; Laminin-5 subunit beta; LAMNB1; Nicein subunit beta; anti-LAMB3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
LAMB3 antibody detects endogenous levels of total LAMB3
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1172
Applicable Applications for anti-LAMB3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide
Subcellular Location
Secreted > Extracellular Space > Extracellular Matrix > Basement Membrane.
Tissue Specificity
Found in the basement membranes (major component).
Predicted Cross Reactivity
Pig, Bovine, Sheep, Rabbit, Dog
Similarity
Pig (100%), Bovine (100%), Sheep (100%), Rabbit (91%), Dog (100%)
Conjugation
Unconjugated
Western Blot (WB)
(Western blot analysis of LAMB3 expression in HEK293 cells, The lane on the left is treated with the antigen-specific peptide.)
Western Blot (WB)
(Western blot analysis of LAMB3 expression in HEK293 cells, The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-LAMB3 antibody
Description: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Subunit Structure: Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Beta-3 is a subunit of laminin-5 (laminin-332 or epiligrin/kalinin/nicein). Interacts with ECM1.
Similarity: The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.Domain VI is globular.
Subunit Structure: Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Beta-3 is a subunit of laminin-5 (laminin-332 or epiligrin/kalinin/nicein). Interacts with ECM1.
Similarity: The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.Domain VI is globular.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 130 kDa
Predicted: 130 kDa
Predicted: 130 kDa
NCBI Official Full Name
laminin subunit beta-3
NCBI Official Synonym Full Names
laminin subunit beta 3
NCBI Official Symbol
LAMB3
NCBI Official Synonym Symbols
AI1A; LAM5; LAMNB1; BM600-125KDA
NCBI Protein Information
laminin subunit beta-3
UniProt Protein Name
Laminin subunit beta-3
Protein Family
UniProt Gene Name
LAMB3
UniProt Synonym Gene Names
LAMNB1
NCBI Description
The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Research Articles on LAMB3
Similar Products
Product Notes
The LAMB3 lamb3 (Catalog #AAA9603896) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LAMB3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LAMB3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the LAMB3 lamb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAMB3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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