Inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1) Recombinant Protein | ITIH1 recombinant protein
Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1)
Gene Names
ITIH1; H1P; ITIH; SHAP; IATIH; IGHEP1; ITI-HC1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1); Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1); ITIH1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
35-672, Full length protein
Sequence
SKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTD
Sequence Length
638
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for ITIH1 recombinant protein
This protein is the heavy chain of a serine protease inhibitor that may serve to carry hyaluronan in plasma. This gene is part of a cluster of similar genes on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69,495 Da
NCBI Official Full Name
inter-alpha-trypsin inhibitor heavy chain H1 isoform b
NCBI Official Synonym Full Names
inter-alpha-trypsin inhibitor heavy chain 1
NCBI Official Symbol
ITIH1
NCBI Official Synonym Symbols
H1P; ITIH; SHAP; IATIH; IGHEP1; ITI-HC1
NCBI Protein Information
inter-alpha-trypsin inhibitor heavy chain H1
UniProt Protein Name
Inter-alpha-trypsin inhibitor heavy chain H1
Protein Family
UniProt Gene Name
ITIH1
UniProt Synonym Gene Names
IGHEP1; ITI heavy chain H1; ITI-HC1; Inter-alpha-inhibitor heavy chain 1; SHAP
NCBI Description
This gene encodes a member of the inter-alpha-trypsin inhibitor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter-alpha-trypsin inhibitor complex, which is secreted by hepatocytes into the blood. The heavy chain also interacts with hyaluronan, and this interaction may play a role in ovulation and fertilization, and has been implicated in multiple inflammatory diseases. This gene is present in a gene cluster on chromosome 3. [provided by RefSeq, Nov 2015]
Uniprot Description
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Research Articles on ITIH1
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Product Notes
The ITIH1 itih1 (Catalog #AAA958289) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 35-672, Full length protein. The amino acid sequence is listed below: SKSSEKRQAV DTAVDGVFIR SLKVNCKVTS RFAHYVVTSQ VVNTANEARE VAFDLEIPKT AFISDFAVTA DGNAFIGDIK DKVTAWKQYR KAAISGENAG LVRASGRTME QFTIHLTVNP QSKVTFQLTY EEVLKRNHMQ YEIVIKVKPK QLVHHFEIDV DIFEPQGISK LDAQASFLPK ELAAQTIKKS FSGKKGHVLF RPTVSQQQSC PTCSTSLLNG HFKVTYDVSR DKICDLLVAN NHFAHFFAPQ NLTNMNKNVV FVIDISGSMR GQKVKQTKEA LLKILGDMQP GDYFDLVLFG TRVQSWKGSL VQASEANLQA AQDFVRGFSL DEATNLNGGL LRGIEILNQV QESLPELSNH ASILIMLTDG DPTEGVTDRS QILKNVRNAI RGRFPLYNLG FGHNVDFNFL EVMSMENNGR AQRIYEDHDA TQQLQGFYSQ VAKPLLVDVD LQYPQDAVLA LTQNHHKQYY EGSEIVVAGR IADNKQSSFK ADVQAHGEGQ EFSITCLVDE EEMKKLLRER GHMLENHVER LWAYLTIQEL LAKRMKVDRE ERANLSSQAL QMSLDYGFVT PLTSMSIRGM ADQDGLKPTI DKPSEDSPPL EMLGPRRTFV LSALQPSPTH SSSNTQRLPD RVTGVDTD. It is sometimes possible for the material contained within the vial of "Inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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