Cytochrome b-245 heavy chain (CYBB) Recombinant Protein | GP91-PHOX recombinant protein
Recombinant Pig Cytochrome b-245 heavy chain (CYBB)
Gene Names
GP91-PHOX; CYBB; NOX2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Cytochrome b-245 heavy chain (CYBB); Recombinant Pig Cytochrome b-245 heavy chain (CYBB); Recombinant Cytochrome b-245 heavy chain (CYBB); Cytochrome b-245 heavy chain EC= 1.-.-.-; CGD91-phox Cytochrome b(558) subunit beta; Cytochrome b558 subunit beta Heme-binding membrane glycoprotein gp91phox Neutrophil cytochrome b 91 kDa polypeptide gp91-; GP91-PHOX recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-484
Sequence
STRVRRQLDRNLTFHKMVAWMIALHATIHTIAHLFNVEWCVNARVNNSDPYSIALSDIGDKPNETYLNFVRQRIKNPEGGLYVAVTRLAGITGVVITLCLILIITSSTKTIRRSYFEVFWYTHHLFVIFFIGLAIHGAERIVRRQTPKSLLVHDPKACAQNISQWGKIKDCPIPEFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQQKVVITKVVTHPFKTIELQMKKKGFRMEVGQYIFVKRPAVSKLEWHPFTLTSAPEEDFFSIHIRIVGDWTEGLFKACGCDKQEFQDAWKLPKIAVDGPFGTASEDVFSYQVVMLVGAGIGVTPFASILKSVWYKYCNNATNLRLKKIYFYWLCRDTHAFEWFADLLQLLETQMQERNNAGFLSYNIYLTGWDESQANHFAVHHDEEKDVITGLKQKTLYGRPNWDNEFKTIASQHPTTRIGVFLCGPEALAETLNKQCISNSDSSPRGVHFIFNKENF
Sequence Length
468
Species
Sus scrofa (Pig)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
55,830 Da
NCBI Official Full Name
cytochrome b-245 heavy chain
NCBI Official Symbol
GP91-PHOX
NCBI Official Synonym Symbols
CYBB; NOX2
NCBI Protein Information
cytochrome b-245 heavy chain; gp91-1; CGD91-phox; p22 phagocyte B-cytochrome; cytochrome b558 subunit beta; neutrophil cytochrome b 91 kDa polypeptide; heme-binding membrane glycoprotein gp91phox
UniProt Protein Name
Cytochrome b-245 heavy chain
UniProt Gene Name
CYBB
UniProt Synonym Gene Names
Cytochrome b558 subunit beta
UniProt Entry Name
CY24B_PIG
Uniprot Description
Function: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes.
Cofactor: FAD
Probable.
Subunit structure: Composed of a heavy chain (beta) and a light chain (alpha). Interacts with calprotectin (S100A8/9)
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Sequence similarities: Contains 1 FAD-binding FR-type domain.Contains 1 ferric oxidoreductase domain.
Sequence caution: The sequence AAA64634.1 differs from that shown. Reason: Erroneous initiation.
Research Articles on GP91-PHOX
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Product Notes
The GP91-PHOX cybb (Catalog #AAA957492) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-484. The amino acid sequence is listed below: STRVRRQLDR NLTFHKMVAW MIALHATIHT IAHLFNVEWC VNARVNNSDP YSIALSDIGD KPNETYLNFV RQRIKNPEGG LYVAVTRLAG ITGVVITLCL ILIITSSTKT IRRSYFEVFW YTHHLFVIFF IGLAIHGAER IVRRQTPKSL LVHDPKACAQ NISQWGKIKD CPIPEFAGNP PMTWKWIVGP MFLYLCERLV RFWRSQQKVV ITKVVTHPFK TIELQMKKKG FRMEVGQYIF VKRPAVSKLE WHPFTLTSAP EEDFFSIHIR IVGDWTEGLF KACGCDKQEF QDAWKLPKIA VDGPFGTASE DVFSYQVVML VGAGIGVTPF ASILKSVWYK YCNNATNLRL KKIYFYWLCR DTHAFEWFAD LLQLLETQMQ ERNNAGFLSY NIYLTGWDES QANHFAVHHD EEKDVITGLK QKTLYGRPNW DNEFKTIASQ HPTTRIGVFL CGPEALAETL NKQCISNSDS SPRGVHFIFN KENF. It is sometimes possible for the material contained within the vial of "Cytochrome b-245 heavy chain (CYBB), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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