Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3) Recombinant Protein | EIF2S3 recombinant protein
Recombinant Human Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit. [provided by RefSeq, Jan 2010]
Uniprot Description
As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In order for eIF2 to recycle and catalyze another round of initiation, the GDP bound to eIF2 must exchange with GTP by way of a reaction catalyzed by eIF2B (). Along with its paralog on chromosome Y, may contribute to spermatogenesis up to the round spermatid stage ().
Research Articles on EIF2S3
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Product Notes
The EIF2S3 eif2s3 (Catalog #AAA957287) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-472, Full length protein. The amino acid sequence is listed below: AGGEAGVTLG QPHLSRQDLT TLDVTKLTPL SHEVISRQAT INIGTIGHVA HGKSTVVKAI SGVHTVRFKN ELERNITIKL GYANAKIYKL DDPSCPRPEC YRSCGSSTPD EFPTDIPGTK GNFKLVRHVS FVDCPGHDIL MATMLNGAAV MDAALLLIAG NESCPQPQTS EHLAAIEIMK LKHILILQNK IDLVKESQAK EQYEQILAFV QGTVAEGAPI IPISAQLKYN IEVVCEYIVK KIPVPPRDFT SEPRLIVIRS FDVNKPGCEV DDLKGGVAGG SILKGVLKVG QEIEVRPGIV SKDSEGKLMC KPIFSKIVSL FAEHNDLQYA APGGLIGVGT KIDPTLCRAD RMVGQVLGAV GALPEIFTEL EISYFLLRRL LGVRTEGDKK AAKVQKLSKN EVLMVNIGSL STGGRVSAVK ADLGKIVLTN PVCTEVGEKI ALSRRVEKHW RLIGWGQIRR GVTIKPTVDD D. It is sometimes possible for the material contained within the vial of "Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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