Rabbit anti-Mouse, Rat Caspase 6 Polyclonal Antibody | anti-Casp6 antibody
Caspase 6 (Cleaved-Asp162) Antibody
Gene Names
Casp6; Mch2; CASP-6
Reactivity
Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Synonyms
Caspase 6; Polyclonal Antibody; Caspase 6 (Cleaved-Asp162) Antibody; Caspase-6; CASP-6; Apoptotic protease Mch-2; CASP6; MCH2; anti-Casp6 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Specificity
Caspase 6 (Cleaved-Asp162) Antibody detects endogenous levels of fragment of activated Caspase 6 resulting from cleavage adjacent to Asp162.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
276
Applicable Applications for anti-Casp6 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000
IHC: 1:50~1:100
ELISA: 1:10000
Target Modification
Cleaved
Immunogen
The antiserum was produced against synthesized peptide derived from mouse Caspase 6.
Immunogen Range
144-193
Preparation and Storage
Stable at -20 degree C for at least 1 year.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28; 35 kDa
NCBI Official Full Name
caspase-6
NCBI Official Synonym Full Names
caspase 6
NCBI Official Symbol
Casp6
NCBI Official Synonym Symbols
Mch2; CASP-6
NCBI Protein Information
caspase-6
UniProt Protein Name
Caspase-6
Protein Family
UniProt Gene Name
Casp6
UniProt Synonym Gene Names
CASP-6
NCBI Description
This gene encodes a member of the cysteine proteases that plays important roles in regulating apoptosis and neurodegeneration. The encoded protein is involved in the transmission of pain and axonal degeneration. Genetic deletion of this gene in mice results in the delay of axon pruning and protects from axon degeneration. [provided by RefSeq, Apr 2015]
Uniprot Description
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death ().
Research Articles on Casp6
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Product Notes
The Casp6 casp6 (Catalog #AAA9508410) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Caspase 6 (Cleaved-Asp162) Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Caspase 6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000. Researchers should empirically determine the suitability of the Casp6 casp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Caspase 6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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