Rabbit anti-Human, Mouse DDX19B Polyclonal Antibody | anti-DDX19B antibody

DDX19B Antibody

Cat. Num. AAA9506073

• Gene Names: DDX19B; DBP5; RNAh; DDX19
• Reactivity: Human, Mouse
• Applications: Western Blot, ELISA
• Purity: Purified from rabbit antiserum by affinity-chromatography using immunogen.
• Synonyms: DDX19B; Polyclonal Antibody; DDX19B Antibody; ATP-dependent RNA helicase DDX19B; DEAD box protein 19B; DEAD box RNA helicase DEAD5; anti-DDX19B antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: DDX19B Antibody detects endogenous levels of total DDX19B protein.
• Purity/Purification: Purified from rabbit antiserum by affinity-chromatography using immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 453

• Applicable Applications for anti-DDX19B antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500~1:1000; ELISA: 1:10000
• Target Modification: Unmodified/Total
• Immunogen: The antiserum was produced against synthesized peptide derived from human DDX19B.
• Immunogen Range: Jan-50
• Preparation and Storage: Stable at -20 degree C for at least 1 year.

Western Blot (WB)

(Western blot analysis of lysates from HT-29 cells, using DDX19B Antibody. The lane on the right is blocked with the synthesized peptide.)

NCBI and Uniprot Product Information

• NCBI GI #: 62241022
• NCBI GeneID: 11269
• NCBI Accession #: NP_001014449.1
• NCBI GenBank Nucleotide #: NM_001014449.2
• UniProt Accession #: Q9UMR2; Q6FIB7; Q6IAE0; Q96KE7; Q9H0U0; B3KNE9; B4DXS6; E7EMK4
• Molecular Weight: 53 kDa
• NCBI Official Full Name: ATP-dependent RNA helicase DDX19B isoform 3
• NCBI Official Synonym Full Names: DEAD-box helicase 19B
• NCBI Official Symbol: DDX19B
• NCBI Official Synonym Symbols: DBP5; RNAh; DDX19
• NCBI Protein Information: ATP-dependent RNA helicase DDX19B
• UniProt Protein Name: ATP-dependent RNA helicase DDX19B
• Protein Family: ATP-dependent RNA helicase
• UniProt Gene Name: DDX19B
• UniProt Synonym Gene Names: DBP5; DDX19; TDBP

NCBI Description

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins.