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Western Blot (WB) (Western blot analysis of extracts from HT-29 cells, using DDX19B antibody.)

Rabbit anti-Human, Mouse DDX19B Polyclonal Antibody | anti-DDX19B antibody

DDX19B Antibody

Gene Names
DDX19B; DBP5; RNAh; DDX19
Reactivity
Human, Mouse
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
DDX19B; Polyclonal Antibody; DDX19B Antibody; ATP-dependent RNA helicase DDX19B; DBP5; DD19B; DDX19; DEAD (Asp-Glu-Ala-As) box 19B; anti-DDX19B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total DDX19B protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
370
Applicable Applications for anti-DDX19B antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500~1:3000
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human DDX19B.
Target Name
DDX19B
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from HT-29 cells, using DDX19B antibody.)

Western Blot (WB) (Western blot analysis of extracts from HT-29 cells, using DDX19B antibody.)
Related Product Information for anti-DDX19B antibody
ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins.Schmitt C., EMBO J. 18:4332-4347(1999).Wiemann S., Genome Res. 11:422-435(2001).Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Product Categories/Family for anti-DDX19B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,063 Da
NCBI Official Full Name
ATP-dependent RNA helicase DDX19B isoform 3
NCBI Official Synonym Full Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
NCBI Official Symbol
DDX19B
NCBI Official Synonym Symbols
DBP5; RNAh; DDX19
NCBI Protein Information
ATP-dependent RNA helicase DDX19B
UniProt Protein Name
ATP-dependent RNA helicase DDX19B
UniProt Gene Name
DDX19B
UniProt Synonym Gene Names
DBP5; DDX19; TDBP
UniProt Entry Name
DD19B_HUMAN

NCBI Description

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

DDX19B: ATP-dependent RNA helicase involved in mRNA export from the nucleus. Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Helicase; EC 3.6.4.13

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: nuclear membrane; membrane; cytoplasm; nuclear pore; nuclear envelope

Molecular Function: RNA binding; helicase activity; ATP binding

Biological Process: protein transport; mRNA export from nucleus

Research Articles on DDX19B

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Product Notes

The DDX19B ddx19b (Catalog #AAA9409148) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DDX19B Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DDX19B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the DDX19B ddx19b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DDX19B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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