Testing Data
(The TFact DLX3 DNA-Binding ELISA detects active DLX3 in SK-N-AS Nuclear Extract. The SK-N-AS cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract.)
Human, Mouse DLX3 ELISA Kit | DLX3 elisa kit
DLX3 TFact DNA-Binding ELISA Kit
Testing Data
(The TFact DLX3 DNA-Binding ELISA detects active DLX3 in SK-N-AS Nuclear Extract. The SK-N-AS cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract.)
Testing Data
(The TFact DLX3 DNA-Binding ELISA detects active DLX3 in SK-N-AS Nuclear Extract. The SK-N-AS cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract.)
NCBI and Uniprot Product Information
NCBI Description
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17. Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism. [provided by RefSeq, Jul 2008]
Uniprot Description
DLX3: Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis. Defects in DLX3 are a cause of trichodentoosseous syndrome (TDO). TDO is an autosomal dominant syndrome characterized by enamel hypoplasia and hypocalcification with associated strikingly curly hair. Defects in DLX3 are the cause of amelogenesis imperfecta type 4 (AI4); also known as amelogenesis imperfecta hypomaturation-hypoplastic type with taurodontism. AI4 is an autosomal dominant defect of enamel formation associated with enlarged pulp chambers. Belongs to the distal-less homeobox family.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 17q21.33
Cellular Component: nucleus
Molecular Function: chromatin binding; DNA binding transcription factor activity; protein binding; sequence-specific DNA binding
Biological Process: blood vessel development; odontoblast differentiation; odontogenesis of dentine-containing teeth; placenta development; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter
Disease: Amelogenesis Imperfecta, Type Iv; Trichodentoosseous Syndrome
Research Articles on DLX3
Similar Products
Product Notes
The Human, Mouse DLX3 dlx3 (Catalog #AAA9502317) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502317 ELISA Kit recognizes Human, Mouse DLX3. It is sometimes possible for the material contained within the vial of "DLX3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
