Claudin 7 ELISA Kit | CLDN7 elisa kit
Claudin 7 Colorimetric Cell-Based ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010]
Uniprot Description
Claudin-7: Plays a major role in tight junction-specific obliteration of the intercellular space. Belongs to the claudin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component: apicolateral plasma membrane; basolateral plasma membrane; bicellular tight junction; integral component of membrane; lateral plasma membrane; plasma membrane
Molecular Function: cell adhesion molecule binding; identical protein binding; protein binding; structural molecule activity
Biological Process: calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; negative regulation of apoptosis; negative regulation of cell adhesion; negative regulation of protein homooligomerization; positive regulation of cell motility; positive regulation of cell proliferation; response to ethanol
Research Articles on CLDN7
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Product Notes
The Human, Mouse, Rat CLDN7 cldn7 (Catalog #AAA9500130) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9500130 ELISA Kit recognizes Human, Mouse, Rat CLDN7. It is sometimes possible for the material contained within the vial of "Claudin 7, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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