Eosinophil peroxidase (EPX) Recombinant Protein | EPX recombinant protein
Recombinant Pig Eosinophil peroxidase (EPX)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Eosinophil peroxidase (EPX); Recombinant Pig Eosinophil peroxidase (EPX); Recombinant Eosinophil peroxidase (EPX); Eosinophil peroxidase; EPO EC= 1.11.1.7 Cleaved into the following 2 chains: 1. Eosinophil peroxidase light chain 2. Eosinophil peroxidase heavy chain; EPX recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-13aa; Full length protein
Sequence
GDKYRXIXGR XNN
Sequence Length
38
Species
Sus scrofa (Pig)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Related Product Information for EPX recombinant protein
This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded precursor protein is processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a cluster of three peroxidase genes at chromosome 17q23. Mutations in this gene result in eosinophil peroxidase deficiency.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
4,342 Da
NCBI Official Full Name
Eosinophil peroxidase
UniProt Protein Name
Eosinophil peroxidase
Protein Family
UniProt Gene Name
EPX
UniProt Synonym Gene Names
EPER; EPO
UniProt Entry Name
PERE_PIG
Uniprot Description
Function: Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils
By similarity.
Catalytic activity: 2 phenolic donor + H2O2 = 2 phenoxyl radical of the donor + 2 H2O.
Cofactor: Binds 1 calcium ion per heterodimer
By similarity.Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer
By similarity.
Subunit structure: Tetramer of two light chains and two heavy chains
By similarity.
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of eosinophils.
Sequence similarities: Belongs to the peroxidase family. XPO subfamily.
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Product Notes
The Eosinophil peroxidase (EPX) epx (Catalog #AAA949256) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-13aa; Full length protein. The amino acid sequence is listed below: GDKYRXIXGR XNN. It is sometimes possible for the material contained within the vial of "Eosinophil peroxidase (EPX), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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