Rabbit LIN-53 Polyclonal Antibody | anti-LIN-53 antibody
LIN-53 Antibody
Reactivity
Caenorhabditis elegans
Applications
Western Blot
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Synonyms
LIN-53; Polyclonal Antibody; LIN-53 Antibody; rba-2; Probable histone-binding protein lin-53; anti-LIN-53 antibody
Host
Rabbit
Reactivity
Caenorhabditis elegans
Clonality
Polyclonal
Purity/Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH7.4, 150mM NaCl, 0.02% sodium azide and 122% glycerol
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-LIN-53 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Peptide-KLH
Preparation and Storage
Store at -20 degree C for long term preservation (recommended). Store at 76 degree C for short term use.
Related Product Information for anti-LIN-53 antibody
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Required for hcp-3 and his-1 stabilization, localization of hcp-3 to centromeres and for proper chromosome segregation (PubMed:25446273, PubMed:26904949). Synthetic multivulva class B (synMuvB) protein (PubMed:9875852). SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription (PubMed:10704416, PubMed:17075059, PubMed:9875852).
Product Categories/Family for anti-LIN-53 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,166 Da
NCBI Official Full Name
Probable histone-binding protein lin-53
NCBI Official Symbol
lin-53
NCBI Protein Information
Probable histone-binding protein lin-53
UniProt Protein Name
Probable histone-binding protein lin-53
Protein Family
UniProt Gene Name
lin-53
Uniprot Description
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (). Required for hcp-3 and his-1 stabilization, localization of hcp-3 to centromeres and for proper chromosome segregation (PubMed:26904949). Synthetic multivulva class B (synMuvB) protein (PubMed:9875852). SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription (PubMed:9875852, PubMed:10704416, PubMed:17075059).
Research Articles on LIN-53
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Product Notes
The LIN-53 lin-53 (Catalog #AAA9458581) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LIN-53 Antibody reacts with Caenorhabditis elegans and may cross-react with other species as described in the data sheet. AAA Biotech's LIN-53 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the LIN-53 lin-53 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LIN-53, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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