Rabbit anti-Human, Mouse L3MBTL3 Polyclonal Antibody | anti-L3MBTL3 antibody
L3MBTL3 Polyclonal Antibody
IF: 1:50-1:100
IP: 1:50-1:200
NCBI and Uniprot Product Information
Uniprot Description
L3MBTL3: a Polycomb group (PcG) protein that regulates the maturation of myeloid progenitor cells. May influence myelopoiesis by transiently enhancing p57(KIP2) expression levels. PcG proteins participate in DNA-binding complexes with gene-repressing activity, many of which have been highlighted for their involvement in hematopoiesis. A member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. Contains a SAM domain, a common protein modules found in eukaryotic proteomes. Many SAM domains have been shown to form helical polymer structures. May create large protein complexes in the cell. Two isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription regulation
Chromosomal Location of Human Ortholog: 6q23
Cellular Component: nucleus
Biological Process: erythrocyte maturation; macrophage differentiation; regulation of transcription, DNA-dependent; granulocyte differentiation; transcription, DNA-dependent; chromatin modification
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Product Notes
The L3MBTL3 l3mbtl3 (Catalog #AAA9434011) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The L3MBTL3 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's L3MBTL3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP). WB: 1:500-1:2000 IF: 1:50-1:100 IP: 1:50-1:200. Researchers should empirically determine the suitability of the L3MBTL3 l3mbtl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "L3MBTL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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