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Western Blot (WB) (Western blot analysis of Phospho-p56 Dok-2 (Tyr402) in lysates of K562?, using Phospho-p56 Dok-2 (Tyr402) Antibody(12996).)

Rabbit anti-Human p56 Dok-2 Polyclonal Antibody | anti-p56 Dok-2 antibody

p56 Dok-2 (Phospho-Tyr402) Antibody

Gene Names
DOK2; p56DOK; p56dok-2
Reactivity
Human
Applications
Western Blot
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Synonyms
p56 Dok-2; Polyclonal Antibody; p56 Dok-2 (Phospho-Tyr402) Antibody; Docking protein 2 56kDa; Docking protein 2; DOK 2; DOK R; DOK2; DOK2_HUMAN; Downstream of tyrosine kinase 2; OTTHUMP00000161710; OTTHUMP00000224923; p56(dok 2); p56(dok-2); p56dok 2; p56DOK; p56dok2;; anti-p56 Dok-2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Phospho-p56 Dok-2 (Phospho-Tyr402) Antibody detects endogenous levels of p56 Dok-2 only when phosphorylated at Tyr402
Purity/Purification
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
412
Applicable Applications for anti-p56 Dok-2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide derived from human p56 Dok-2 around the phosphorylation site of Tyr402
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.

Western Blot (WB)

(Western blot analysis of Phospho-p56 Dok-2 (Tyr402) in lysates of K562?, using Phospho-p56 Dok-2 (Tyr402) Antibody(12996).)

Western Blot (WB) (Western blot analysis of Phospho-p56 Dok-2 (Tyr402) in lysates of K562?, using Phospho-p56 Dok-2 (Tyr402) Antibody(12996).)
Product Categories/Family for anti-p56 Dok-2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56
NCBI Official Full Name
docking protein 2 isoform a
NCBI Official Synonym Full Names
docking protein 2
NCBI Official Symbol
DOK2
NCBI Official Synonym Symbols
p56DOK; p56dok-2
NCBI Protein Information
docking protein 2
UniProt Protein Name
Docking protein 2
UniProt Gene Name
DOK2

NCBI Description

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]

Uniprot Description

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation ().

Research Articles on p56 Dok-2

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Product Notes

The p56 Dok-2 dok2 (Catalog #AAA9429148) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The p56 Dok-2 (Phospho-Tyr402) Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's p56 Dok-2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the p56 Dok-2 dok2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p56 Dok-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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