Mouse Transcriptional repressor CTCF ELISA Kit | Ctcf elisa kit
Mouse Transcriptional repressor CTCF ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
CTCF: a widely expressed, sequence-specific DNA-binding transcriptional regulator, insulator, and organizer of higher-order chromatin structure. Acts as a tumor suppressor. Contains 11 C2H2-type zinc fingers. Involved in promoter activation or repression, hormone-responsive gene silencing, methylation-dependent chromatin insulation, and genomic imprinting. Mediates pairing between X chromosomes and interactions between distant regulatory elements. Binds to promoters of c-myc, PLK, PIM1 and APP. A critical regulator of cell-cycle arrest and death after B cell receptor signaling in immature B cells. CTCF, together with YY1 and Tsix, form a regulated epigenetic switch for X-inactivation.
Protein type: C2H2-type zinc finger protein; Transcription factor; Tumor suppressor
Chromosomal Location of Human Ortholog: 8|8 D3
Cellular Component: chromosome, pericentric region; condensed chromosome; nucleolus; nucleoplasm; nucleus
Molecular Function: chromatin binding; chromatin insulator sequence binding; DNA binding; protein binding; sequence-specific DNA binding; transcription factor activity
Biological Process: DNA methylation; dosage compensation, by inactivation of X chromosome; genetic imprinting; maintenance of DNA methylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; nucleosome positioning; positive regulation of transcription, DNA-dependent; regulation of gene expression, epigenetic; regulation of histone acetylation; regulation of histone methylation; regulation of molecular function, epigenetic; regulation of transcription, DNA-dependent
Research Articles on Ctcf
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Product Notes
The Mouse Ctcf ctcf (Catalog #AAA9428355) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9428355 ELISA Kit recognizes Mouse Ctcf. It is sometimes possible for the material contained within the vial of "Transcriptional repressor CTCF, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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