Human Putative alpha-1-antitrypsin-related protein ELISA Kit | SERPINA2 elisa kit
Human Putative alpha-1-antitrypsin-related protein ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. The encoded intracellular glycoprotein is localized at the endoplasmic reticulum. This gene is a polymorphic pseudogene, with the non-functional allele being predominant in some populations. Some individuals, as represented by the reference genome allele, contain a 2kb coding region deletion and a start code mutation. [provided by RefSeq, Feb 2014]
Uniprot Description
SERPINA2: NCBI Note: Population studies indicate that this gene is polymorphic. Deletions, frameshift mutations and a critical start codon mutation (ATG->ATA) have been found in some populations as well as an allele that can encode a functional protein. This gene may be an evolving pseudogene (PMID: 17135331). The reference genome contains the start codon mutation and has a coding region deletion. The NCBI RefSeq Project therefore treats this as a pseudogene. [31 Jan 2012]
Chromosomal Location of Human Ortholog: 14q32.13
Cellular Component: endoplasmic reticulum; extracellular space
Molecular Function: protein binding; serine-type endopeptidase inhibitor activity
Research Articles on SERPINA2
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Product Notes
The Human SERPINA2 serpina2 (Catalog #AAA9427376) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9427376 ELISA Kit recognizes Human SERPINA2. It is sometimes possible for the material contained within the vial of "Putative alpha-1-antitrypsin-related protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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