Bovine Chitinase-3-like protein 1 ELISA Kit | CHI3L1 elisa kit

Bovine Chitinase-3-like protein 1 ELISA Kit

Cat. Num. AAA9427274

• Gene Names: CHI3L1; CLP-1; GP-39; CGP-39; SPC-40; SPS-40; YKL-40
• Reactivity: Bovine
• Synonyms: Chitinase-3-like protein 1; Bovine Chitinase-3-like protein 1 ELISA Kit; 39 kDa whey protein; Cartilage glycoprotein 39; CGP-39; GP-39; Chitinase-like protein 1; CLP-1; SPC-40; Signal-processing protein; CHI3L1; CHI3L1 elisa kit

• Reactivity: Bovine

• Samples: Serum, plasma, tissue homogenates and other biological fluids.
• Detection Range: 0.78-50 ng/mL
• Assay Time: 3-5h
• Sample Volume: 100T
• Detection Wavelength: 450 nm
• Preparation and Storage: Store at 4 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 122692297
• NCBI GeneID: 286869
• NCBI Accession #: NP_001073688.1
• NCBI GenBank Nucleotide #: NM_001080219.1
• UniProt Accession #: P30922; O18949; Q58CW2; Q7YSE8
• Molecular Weight: 43,032 Da
• NCBI Official Full Name: chitinase-3-like protein 1
• NCBI Official Symbol: CHI3L1
• NCBI Official Synonym Symbols: CLP-1; GP-39; CGP-39; SPC-40; SPS-40; YKL-40
• NCBI Protein Information: chitinase-3-like protein 1
• UniProt Protein Name: Chitinase-3-like protein 1
• Protein Family: Chitinase-3-like protein
• UniProt Gene Name: CHI3L1
• UniProt Synonym Gene Names: CGP-39; GP-39; CLP-1

Uniprot Description

Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung ().