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Human Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1C ELISA Kit | PDE1C elisa kit

Human Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1C ELISA Kit

Gene Names
PDE1C; Hcam3; hCam-3; cam-PDE 1C
Reactivity
Human
Synonyms
Calcium/calmodulin-dependent 3'; 5'-cyclic nucleotide phosphodiesterase 1C; Human Calcium/calmodulin-dependent 3'; 5'-cyclic nucleotide phosphodiesterase 1C ELISA Kit; Cam-PDE 1C; hCam-3; PDE1C; 3.1.4.17; PDE1C elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Samples
Serum, plasma, tissue homogenates and other biological fluids.
Detection Range
0.156-10 ng/mL
Sensitivity
Less than 0.15ng/mL
Assay Time
3-5h
Sample Volume
100T
Detection Wavelength
450 nm
Preparation and Storage
Store at 4 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
86,896 Da
NCBI Official Full Name
calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform 1
NCBI Official Synonym Full Names
phosphodiesterase 1C
NCBI Official Symbol
PDE1C
NCBI Official Synonym Symbols
Hcam3; hCam-3; cam-PDE 1C
NCBI Protein Information
calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
UniProt Protein Name
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
UniProt Gene Name
PDE1C
UniProt Synonym Gene Names
Cam-PDE 1C

NCBI Description

This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016]

Uniprot Description

PDE1C: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.4.17; Nucleotide Metabolism - purine; Phosphodiesterase

Chromosomal Location of Human Ortholog: 7p14.3

Cellular Component: cytosol

Molecular Function: calmodulin-dependent cyclic-nucleotide phosphodiesterase activity

Research Articles on PDE1C

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Product Notes

The Human PDE1C pde1c (Catalog #AAA9426771) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9426771 ELISA Kit recognizes Human PDE1C. It is sometimes possible for the material contained within the vial of "Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1C, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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