Mouse Interleukin-12 subunit alpha ELISA Kit | Il12a elisa kit

Mouse Interleukin-12 subunit alpha ELISA Kit

Gene Names

Il12a; p35; Ll12a; Il-12a; IL-12p35

Reactivity

Mouse

Synonyms

Interleukin-12 subunit alpha; Mouse Interleukin-12 subunit alpha ELISA Kit; IL-12A; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Il12a; Il12a elisa kit

Ordering
Cat. Num. AAA9425033 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Mouse

Samples

Serum, plasma, tissue homogenates and other biological fluids.

Detection Range

0.156-10 ng/mL

Assay Time

3-5h

Sample Volume

100T

Detection Wavelength

450 nm

Preparation and Storage

Store at 4 degree C

NCBI and Uniprot Product Information

NCBI GI #

226874945

NCBI GeneID

16159

NCBI Accession #

NP_001152896.1

NCBI GenBank Nucleotide #

NM_001159424.2

UniProt Accession #

P43431

Molecular Weight

24,179 Da

NCBI Official Full Name

interleukin-12 subunit alpha isoform 1

NCBI Official Synonym Full Names

interleukin 12a

NCBI Official Symbol

Il12a

NCBI Official Synonym Symbols

p35; Ll12a; Il-12a; IL-12p35

NCBI Protein Information

interleukin-12 subunit alpha

UniProt Protein Name

Interleukin-12 subunit alpha

Protein Family

Interleukin

UniProt Gene Name

Il12a

UniProt Synonym Gene Names

IL-12A; CLMF p35

Uniprot Description

IL12A: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-6 superfamily.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3 E1|3 31.92 cM

Cellular Component: cytoplasm; extracellular space; interleukin-12 complex

Molecular Function: cytokine activity; growth factor activity; interleukin-12 beta subunit binding; interleukin-27 binding; protein heterodimerization activity

Biological Process: cell cycle arrest; cell migration; defense response to protozoan; negative regulation of interleukin-17 production; negative regulation of smooth muscle cell proliferation; positive regulation of cell adhesion; positive regulation of interferon-gamma production; positive regulation of lymphocyte proliferation; positive regulation of mononuclear cell proliferation; positive regulation of natural killer cell activation; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; positive regulation of NK T cell activation; positive regulation of T cell differentiation; positive regulation of T cell mediated cytotoxicity; positive regulation of T cell proliferation; positive regulation of tyrosine phosphorylation of STAT protein; response to lipopolysaccharide; response to UV-B

Research Articles on Il12a

1. this study shows that a systemic IL-12 primes intestinal cells that became more prone to develop inflammatory responses, which is long-lasting because intestinal cells maintain their inflammatory potential and their ability to aggravate colitis

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Product Notes

The Mouse Il12a il12a (Catalog #AAA9425033) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9425033 ELISA Kit recognizes Mouse Il12a. It is sometimes possible for the material contained within the vial of "Interleukin-12 subunit alpha, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Mouse Interleukin-12 subunit alpha ELISA Kit | Il12a elisa kit