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Clathrin interactor 1 (CLINT1) Recombinant Protein | CLINT1 recombinant protein

Recombinant Human Clathrin interactor 1 (CLINT1)

Gene Names
CLINT1; ENTH; EPN4; EPNR; CLINT
Reactivity
Human
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Clathrin interactor 1 (CLINT1); Recombinant Human Clathrin interactor 1 (CLINT1); Clathrin-interacting protein localized in the trans-Golgi region; CLINT1 recombinant protein
Ordering
For Research Use Only!
Host
Yeast
Reactivity
Human
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
Tris-based buffer, 50% glycerol
Sequence Positions
Full Length, 1-625aa
Tag Info
N-terminal 6xHis-tagged
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
70.26 kDa
NCBI Official Full Name
clathrin interactor 1 isoform 1
NCBI Official Synonym Full Names
clathrin interactor 1
NCBI Official Symbol
CLINT1
NCBI Official Synonym Symbols
ENTH; EPN4; EPNR; CLINT
NCBI Protein Information
clathrin interactor 1
UniProt Protein Name
Clathrin interactor 1
Protein Family
UniProt Gene Name
CLINT1
UniProt Synonym Gene Names
ENTH; EPN4; EPNR; KIAA0171; Clint; EpsinR

NCBI Description

This gene encodes a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]

Uniprot Description

ENTH: Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly. Belongs to the epsin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 5q33.3

Cellular Component: cytosol; Golgi apparatus; intracellular membrane-bound organelle; membrane; nucleoplasm

Molecular Function: cadherin binding; clathrin binding; protein binding

Disease: Schizophrenia 1

Research Articles on CLINT1

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Product Notes

The CLINT1 clint1 (Catalog #AAA9424066) is a Recombinant Protein produced from Yeast and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length, 1-625aa. The Recombinant Human Clathrin interactor 1 (CLINT1) reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Clathrin interactor 1 (CLINT1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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