H-2 class I histocompatibility antigen Recombinant Protein | HA1D recombinant protein

Recombinant mouse H-2 class I histocompatibility antigen, K-D alpha chain

Cat. Num. AAA9420987

• Gene Names: H2-K1; K-f; H-2K; H2-K; H-2K(d)
• Reactivity: Mouse
• Purity: Greater than 90% as determined by SDS-PAGE.
• Synonyms: H-2 class I histocompatibility antigen; Recombinant mouse H-2 class I histocompatibility antigen; K-D alpha chain; HA1D recombinant protein

• Host: E Coli
• Reactivity: Mouse
• Purity/Purification: Greater than 90% as determined by SDS-PAGE.
• Form/Format: 20mM Tris-HCl based buffer, pH8.0
• Sequence Positions: Extracellular Domain, 22-305aa

• Tag Info: GST-tag
• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.

Related Product Information for HA1D recombinant protein

Involved in the presentation of foreign antigens to the immune syst.

NCBI and Uniprot Product Information

• NCBI GI #: 122148
• NCBI GeneID: 14972
• UniProt Accession #: P01902; P01901; P04223; P14428; P03991
• Molecular Weight: 60.4kD
• NCBI Official Full Name: H-2 class I histocompatibility antigen, K-D alpha chain
• NCBI Official Synonym Full Names: histocompatibility 2, K1, K region
• NCBI Official Symbol: H2-K1
• NCBI Official Synonym Symbols: K-f; H-2K; H2-K; H-2K(d)
• NCBI Protein Information: H-2 class I histocompatibility antigen, K-W28 alpha chain
• UniProt Protein Name: H-2 class I histocompatibility antigen, K-D alpha chain
• Protein Family: H-2 class I histocompatibility antigen
• UniProt Gene Name: H2-K1
• UniProt Synonym Gene Names: H2-K; H-2K(D)

Uniprot Description

H2-K1(D):

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 17 B1|17 17.98 cM

Cellular Component: cell surface; endoplasmic reticulum; external side of plasma membrane; Golgi apparatus; Golgi medial cisterna; membrane; MHC class I protein complex

Molecular Function: beta-2-microglobulin binding; peptide antigen binding; peptide binding; protein binding; protein heterodimerization activity; receptor binding; RNA binding; T cell receptor binding; TAP binding

Biological Process: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; antigen processing and presentation of exogenous peptide antigen via MHC class I; defense response to bacterium; inner ear development; positive regulation of T cell mediated cytotoxicity