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Western Blot (WB) (Western blot analysis PCDH-X/Y using HeLa whole cell lysates)

Rabbit anti-Human PCDH-X/Y Polyclonal Antibody | anti-PCDH-X/Y antibody

PCDH-X/Y Antibody

Gene Names
PCDH11Y; PCDHX; PCDHY; PCDH22; PCDH-PC
Reactivity
Human
Applications
Western Blot
Synonyms
PCDH-X/Y; Polyclonal Antibody; PCDH-X/Y Antibody; Protocadherin-11; Protocadherin-22; Protocadherin on the Y chromosome; PCDH-Y; Protocadherin prostate cancer; Protocadherin-PC;; anti-PCDH-X/Y antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
PCDH-X/Y Antibody detects endogenous levels of total PCDH-X/Y
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
1037
Applicable Applications for anti-PCDH-X/Y antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000-3000
Immunogen
A synthesized peptide derived from human PCDH-X/Y
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis PCDH-X/Y using HeLa whole cell lysates)

Western Blot (WB) (Western blot analysis PCDH-X/Y using HeLa whole cell lysates)
Product Categories/Family for anti-PCDH-X/Y antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
116,406 Da
NCBI Official Full Name
protocadherin-11 Y-linked isoform a
NCBI Official Synonym Full Names
protocadherin 11 Y-linked
NCBI Official Symbol
PCDH11Y
NCBI Official Synonym Symbols
PCDHX; PCDHY; PCDH22; PCDH-PC
NCBI Protein Information
protocadherin-11 Y-linked
UniProt Protein Name
Protocadherin-11 Y-linked
UniProt Gene Name
PCDH11Y
UniProt Synonym Gene Names
PCDH11; PCDH22; PCDHY; Protocadherin-11; PCDH-Y; Protocadherin-PC
UniProt Entry Name
PC11Y_HUMAN

NCBI Description

This gene belongs to the protocadherin family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing seven cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of the classical cadherins. This gene is located on the Y chromosome in a block of X/Y homology and is very closely related to its paralog on the X chromosome. The protein is thought to play a role in cell-cell recognition during development of the central nervous system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Uniprot Description

PCDH11Y: Potential calcium-dependent cell-adhesion protein. A chromosomal aberration involving PCDH11Y is a cause of multiple congenital abnormalities, including severe bilateral vesicoureteral reflux (VUR) with ureterovesical junction defects. Translocation t(Y;3)(p11;p12) with ROBO2. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Yp11.2

Research Articles on PCDH-X/Y

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Product Notes

The PCDH-X/Y pcdh11y (Catalog #AAA9418943) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PCDH-X/Y Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PCDH-X/Y can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000-3000. Researchers should empirically determine the suitability of the PCDH-X/Y pcdh11y for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PCDH-X/Y, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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