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Western Blot (WB) (Western blot analysis of BCL11B expression in Jurkat cell lysate,The lane on the left is treated with the antigen-specific peptide.)

Rabbit anti-Human BCL11B Polyclonal Antibody | anti-BCL11B antibody

BCL11B Antibody

Gene Names
BCL11B; ATL1; RIT1; CTIP2; IMD49; CTIP-2; ZNF856B; ATL1-beta; ATL1-alpha; ATL1-delta; ATL1-gamma; hRIT1-alpha
Reactivity
Human
Applications
Western Blot
Synonyms
BCL11B; Polyclonal Antibody; BCL11B Antibody; ATL1 alpha antibody; anti-BCL11B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
BCL11Bantibody detects endogenous levels of total BCL11B
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
893
Applicable Applications for anti-BCL11B antibody
Western Blot (WB)
Application Notes
Western Blot: 1:500-1:2000
Immunogen
A synthesized peptide derived from human BCL11B
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of BCL11B expression in Jurkat cell lysate,The lane on the left is treated with the antigen-specific peptide.)

Western Blot (WB) (Western blot analysis of BCL11B expression in Jurkat cell lysate,The lane on the left is treated with the antigen-specific peptide.)
Product Categories/Family for anti-BCL11B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
88,476 Da
NCBI Official Full Name
B-cell lymphoma/leukemia 11B isoform 3
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 11B
NCBI Official Symbol
BCL11B
NCBI Official Synonym Symbols
ATL1; RIT1; CTIP2; IMD49; CTIP-2; ZNF856B; ATL1-beta; ATL1-alpha; ATL1-delta; ATL1-gamma; hRIT1-alpha
NCBI Protein Information
B-cell lymphoma/leukemia 11B
UniProt Protein Name
B-cell lymphoma/leukemia 11B
Protein Family
UniProt Gene Name
BCL11B
UniProt Synonym Gene Names
CTIP2; RIT1; BCL-11B; hRit1
UniProt Entry Name
BC11B_HUMAN

NCBI Description

This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

Uniprot Description

Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element ().

Research Articles on BCL11B

Similar Products

Product Notes

The BCL11B bcl11b (Catalog #AAA9418172) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCL11B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BCL11B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500-1:2000. Researchers should empirically determine the suitability of the BCL11B bcl11b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCL11B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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