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Western Blot (WB) (All lanes: Aspartate aminotransferase, mitochondrial antibody at 2ug/ml)

Rabbit anti-Human Aspartate aminotransferase Polyclonal Antibody | anti-GOT2 antibody

Aspartate aminotransferase, mitochondrial Polyclonal Antibody

Gene Names
GOT2; KAT4; KATIV; mitAAT
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
Aspartate aminotransferase; Polyclonal Antibody; mitochondrial Polyclonal Antibody; GOT2; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A; anti-GOT2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total Aspartate aminotransferase, mitochondrial polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
387
Applicable Applications for anti-GOT2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200
Immunogen
Recombinant Human Aspartate aminotransferase, mitochondrial protein
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(All lanes: Aspartate aminotransferase, mitochondrial antibody at 2ug/ml)

Western Blot (WB) (All lanes: Aspartate aminotransferase, mitochondrial antibody at 2ug/ml)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-emdedded human liver using at dilution of 1:100.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-emdedded human liver using at dilution of 1:100.)
Related Product Information for anti-GOT2 antibody
Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.
Product Categories/Family for anti-GOT2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
43,030 Da
NCBI Official Full Name
aspartate aminotransferase, mitochondrial isoform 2
NCBI Official Synonym Full Names
glutamic-oxaloacetic transaminase 2
NCBI Official Symbol
GOT2
NCBI Official Synonym Symbols
KAT4; KATIV; mitAAT
NCBI Protein Information
aspartate aminotransferase, mitochondrial
UniProt Protein Name
Aspartate aminotransferase, mitochondrial
UniProt Gene Name
GOT2
UniProt Synonym Gene Names
mAspAT; FABP-1; FABPpm
UniProt Entry Name
AATM_HUMAN

Uniprot Description

GOT2: Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - cysteine and methionine; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - phenylalanine, tyrosine and tryptophan biosynthesis; Amino Acid Metabolism - tyrosine; EC 2.6.1.1; EC 2.6.1.7; Mitochondrial; Transferase

Chromosomal Location of Human Ortholog: 16q21

Cellular Component: mitochondrial matrix; mitochondrion; plasma membrane

Molecular Function: aspartate transaminase activity; identical protein binding; pyridoxal phosphate binding

Biological Process: 2-oxoglutarate metabolic process; 4-hydroxyproline catabolic process; amino acid biosynthetic process; aspartate catabolic process; aspartate metabolic process; fatty acid transport; gluconeogenesis; glutamate metabolic process; response to ethanol

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Product Notes

The GOT2 got2 (Catalog #AAA9416307) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Aspartate aminotransferase, mitochondrial Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Aspartate aminotransferase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:500 - 1:1000 Immunohistochemistry: 1:20 - 1:200. Researchers should empirically determine the suitability of the GOT2 got2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Aspartate aminotransferase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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