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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human liver cancer using at dilution of 1:100.)

Rabbit anti-Human Serpin B3 Polyclonal Antibody | anti-SERPINB3 antibody

Serpin B3 Polyclonal Antibody

Gene Names
SERPINB3; SCC; T4-A; SCCA1; SSCA1; SCCA-1; HsT1196; SCCA-PD
Reactivity
Human
Applications
Immunohistochemistry
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
Serpin B3; Polyclonal Antibody; Serpin B3 Polyclonal Antibody; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1; SERPINB3; SCCA; SCCA1; anti-SERPINB3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total Serpin B3 polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
390
Applicable Applications for anti-SERPINB3 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:20 - 1:200
Immunogen
Recombinant Human Serpin B3 protein
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human liver cancer using at dilution of 1:100.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human liver cancer using at dilution of 1:100.)
Related Product Information for anti-SERPINB3 antibody
May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells.Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
Product Categories/Family for anti-SERPINB3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,550 Da
NCBI Official Full Name
serpin B3
NCBI Official Synonym Full Names
serpin family B member 3
NCBI Official Symbol
SERPINB3
NCBI Official Synonym Symbols
SCC; T4-A; SCCA1; SSCA1; SCCA-1; HsT1196; SCCA-PD
NCBI Protein Information
serpin B3
UniProt Protein Name
Serpin B3
Protein Family
UniProt Gene Name
SERPINB3
UniProt Synonym Gene Names
SCCA; SCCA1; SCCA-1
UniProt Entry Name
SPB3_HUMAN

Uniprot Description

SERPINB3: May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 18q21.3

Cellular Component: cytoplasm; cytoplasmic vesicle; extracellular space; nucleus; vesicle

Molecular Function: cysteine protease inhibitor activity; protease binding; serine-type endopeptidase inhibitor activity; viral receptor activity

Biological Process: negative regulation of catalytic activity; negative regulation of JNK activity; negative regulation of peptidase activity; negative regulation of proteolysis; positive regulation of cell migration; positive regulation of cell proliferation

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Product Notes

The SERPINB3 serpinb3 (Catalog #AAA9415797) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Serpin B3 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Serpin B3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:20 - 1:200. Researchers should empirically determine the suitability of the SERPINB3 serpinb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Serpin B3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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