Rabbit anti-Human BMP3 Polyclonal Antibody | anti-BMP3 antibody

BMP3 Antibody

Cat. Num. AAA9414737

• Gene Names: BMP3; BMP-3A
• Reactivity: Human
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: BMP3; Polyclonal Antibody; BMP3 Antibody; Bone morphogenetic protein 3; BMP-3; Osteogenin; BMP-3A; Bone morphogenetic protein 3A; anti-BMP3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total BMP3 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 472

• Applicable Applications for anti-BMP3 antibody: Western Blot (WB)
• Application Notes: Western blotting: 1:500~1:3000
• Immunogen Type: Peptide
• Immunogen Description: Synthesized peptide derived from internal of human BMP3.
• Target Name: BMP3
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from HeLa cells, HuvEc cells and HepG2 cells, using BMP3 antibody.)

Related Product Information for anti-BMP3 antibody

Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.Wozney J.M., Science 242:1528-1534(1988).Hillier L.W., Nature 434:724-731(2005).Daluiski A., Nat. Genet. 27:84-88(2001).

Product Categories/Family for anti-BMP3 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 126507087
• NCBI GeneID: 651
• NCBI Accession #: NP_001192.2
• NCBI GenBank Nucleotide #: NM_001201.2
• UniProt Accession #: P12645; Q4VAS5
• Molecular Weight: 53,372 Da
• NCBI Official Full Name: bone morphogenetic protein 3 preproprotein
• NCBI Official Synonym Full Names: bone morphogenetic protein 3
• NCBI Official Symbol: BMP3
• NCBI Official Synonym Symbols: BMP-3A
• NCBI Protein Information: bone morphogenetic protein 3
• UniProt Protein Name: Bone morphogenetic protein 3
• Protein Family: Bone morphogenetic protein
• UniProt Gene Name: BMP3
• UniProt Synonym Gene Names: BMP3A; BMP-3; BMP-3A
• UniProt Entry Name: BMP3_HUMAN

NCBI Description

BMP3 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein, also known as osteogenin, induces bone formation. [provided by RefSeq, Jul 2008]

Uniprot Description

BMP3: Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted; Cytokine

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding; receptor binding

Biological Process: regulation of apoptosis; ossification; cell-cell signaling; cartilage development; regulation of MAPKKK cascade; positive regulation of transcription from RNA polymerase II promoter; skeletal development; cell development; growth