Testing Data
(Gel: 8%SDS-PAGE Lysates (from left to right): 293T, MCF-7 and PC3 cell, human fetal liver tissue and Hela cell Amount of lysate: 40ug per lane Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 20 seconds)
Rabbit anti-Human ECHS1 Polyclonal Antibody | anti-ECHS1 antibody
ECHS1 Antibody
Immunohistochemistry: 1:25-1:100
Testing Data
(Gel: 8%SDS-PAGE Lysates (from left to right): 293T, MCF-7 and PC3 cell, human fetal liver tissue and Hela cell Amount of lysate: 40ug per lane Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 20 seconds)
Testing Data
(Gel: 8%SDS-PAGE Lysates (from left to right): 293T, MCF-7 and PC3 cell, human fetal liver tissue and Hela cell Amount of lysate: 40ug per lane Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 20 seconds)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using at dilution 1/35.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using at dilution 1/35.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. [provided by RefSeq, Jul 2008]
Uniprot Description
ECHS1: Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. Belongs to the enoyl-CoA hydratase/isomerase family.
Protein type: Other Amino Acids Metabolism - beta-alanine; Carbohydrate Metabolism - butanoate; Carbohydrate Metabolism - propanoate; Amino Acid Metabolism - lysine degradation; Lipid Metabolism - fatty acid; Mitochondrial; Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 4.2.1.17; Secondary Metabolites Metabolism - limonene and pinene degradation; Amino Acid Metabolism - tryptophan; Lipid Metabolism - fatty acid elongation in mitochondria; Lyase
Chromosomal Location of Human Ortholog: 10q26.2-q26.3
Cellular Component: mitochondrion; mitochondrial matrix
Molecular Function: protein binding; enoyl-CoA hydratase activity
Biological Process: fatty acid beta-oxidation; cellular lipid metabolic process
Disease: Mitochondrial Short-chain Enoyl-coa Hydratase 1 Deficiency
Research Articles on ECHS1
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Product Notes
The ECHS1 echs1 (Catalog #AAA9414605) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ECHS1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ECHS1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500-1:2000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the ECHS1 echs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ECHS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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