Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug Mouse intestines tissuePrimary antibody: 1/200 dilution Secondary antibody dilution: 1/8000Exposure time: 2 minutes)
Rabbit anti-Human, Mouse OLFM3 Polyclonal Antibody | anti-OLFM3 antibody
OLFM3 Antibody
Gene Names
OLFM3; NOE3; NOELIN3; OPTIMEDIN
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Antigen affinity purification.
Synonyms
OLFM3; Polyclonal Antibody; OLFM3 Antibody; NOE3; NOELIN3; OPTIMEDIN; anti-OLFM3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total OLFM3 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.1 mg/ml (varies by lot)
Sequence Length
478
Applicable Applications for anti-OLFM3 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:200-1:1000
Immunogen Type
Protein
Immunogen Description
Fusion protein corresponding to residues near the C terminal of human olfactomedin 3
Target Name
OLFM3
Preparation and Storage
Store at -20 degree C
Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug Mouse intestines tissuePrimary antibody: 1/200 dilution Secondary antibody dilution: 1/8000Exposure time: 2 minutes)
Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug Mouse intestines tissuePrimary antibody: 1/200 dilution Secondary antibody dilution: 1/8000Exposure time: 2 minutes)
Related Product Information for anti-OLFM3 antibody
OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.
Product Categories/Family for anti-OLFM3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,790 Da
NCBI Official Full Name
noelin-3 isoform 1
NCBI Official Synonym Full Names
olfactomedin 3
NCBI Official Symbol
OLFM3
NCBI Official Synonym Symbols
NOE3; NOELIN3; OPTIMEDIN
NCBI Protein Information
noelin-3
UniProt Protein Name
Noelin-3
Protein Family
UniProt Gene Name
OLFM3
UniProt Synonym Gene Names
NOE3
UniProt Entry Name
NOE3_HUMAN
Uniprot Description
OLFM3: 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 1p22
Cellular Component: Golgi apparatus; extracellular space; synapse; cell junction
Molecular Function: protein binding
Biological Process: eye photoreceptor cell development
Research Articles on OLFM3
1. This is the first instance of OLFM3 being linked with anoikis resistance in a human cancer cell line
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Product Notes
The OLFM3 olfm3 (Catalog #AAA9412734) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The OLFM3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's OLFM3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:200-1:1000. Researchers should empirically determine the suitability of the OLFM3 olfm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OLFM3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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