Rabbit MTR4 Polyclonal Antibody | anti-MTR4 antibody

MTR4 antibody

Cat. Num. AAA9405945

• Gene Names: SKIV2L2; Dob1; Mtr4; fSAP118; KIAA0052
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Antibodies were purified by affinity purification using immunogen.
• Synonyms: MTR4; Polyclonal Antibody; MTR4 antibody; Dob1; Mtr4; fSAP118; KIAA0052; anti-MTR4 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total MTR4 antibody.
• Purity/Purification: Antibodies were purified by affinity purification using immunogen.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 1042

• Applicable Applications for anti-MTR4 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Western blotting: 1:500 - 1:2000; Immunohistochemistry: 1:50 - 1:200
• Immunogen Type: Recombinant Protein
• Immunogen Description: Recombinant protein of human MTR4.
• Target Name: MTR4
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using MTR4 antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded rat brain tissue using MTR4 antibody at dilution of 1:200 (x400 lens).)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded rat heart tissue using MTR4 antibody at dilution of 1:200 (x400 lens).)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human lung cancer tissue using MTR4 antibody at dilution of 1:200 (x400 lens).)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human kidney cancer tissue using MTR4 antibody at dilution of 1:200 (x400 lens).)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded rat liver tissue using MTR4 antibody at dilution of 1:200 (x400 lens).)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human liver cancer tissue using MTR4 antibody at dilution of 1:200 (x400 lens).)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human embryo brain tissue using MTR4 antibody at dilution of 1:200 (x400 lens).)

Related Product Information for anti-MTR4 antibody

May be involved in pre-mRNA splicing. Associated with the RNA exosome complex and involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA.

Product Categories/Family for anti-MTR4 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 193211480
• NCBI GeneID: 23517
• NCBI Accession #: NP_056175.3
• NCBI GenBank Nucleotide #: NM_015360.4
• UniProt Accession #: P42285; Q2M386; Q6MZZ8; Q6P170; Q8N5R0; Q8TAG2
• Molecular Weight: 117,805 Da
• NCBI Official Full Name: superkiller viralicidic activity 2-like 2
• NCBI Official Synonym Full Names: superkiller viralicidic activity 2-like 2 (S. cerevisiae)
• NCBI Official Symbol: SKIV2L2
• NCBI Official Synonym Symbols: Dob1; Mtr4; fSAP118; KIAA0052
• NCBI Protein Information: superkiller viralicidic activity 2-like 2
• UniProt Protein Name: Superkiller viralicidic activity 2-like 2
• Protein Family: ATP-dependent RNA helicase
• UniProt Gene Name: SKIV2L2
• UniProt Synonym Gene Names: KIAA0052; Mtr4
• UniProt Entry Name: SK2L2_HUMAN

Uniprot Description

SKIV2L2: May be involved in pre-mRNA splicing. Associated with the RNA exosome complex and involved in the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Belongs to the helicase family. SKI2 subfamily.

Protein type: Helicase; EC 3.6.4.13; Nucleolus; DNA-binding; Spliceosome

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: nucleoplasm; nucleolus; exosome (RNase complex); nucleus

Molecular Function: protein binding; helicase activity; ATP binding

Biological Process: nuclear mRNA splicing, via spliceosome; maturation of 5.8S rRNA