Testing Data
(Gel: 8%SDS-PAGE Lysates (from left to right): Human lung cancer tissue Amount of lysate: 40ug per lane Primary antibody: 1/550 dilution Secondary antibody dilution: 1/8000 Exposure time: 40 seconds)
Rabbit anti-Human CALCRL Polyclonal Antibody | anti-CALCRL antibody
CALCRL Antibody
Immunohistochemistry: 1:50-1:200
Testing Data
(Gel: 8%SDS-PAGE Lysates (from left to right): Human lung cancer tissue Amount of lysate: 40ug per lane Primary antibody: 1/550 dilution Secondary antibody dilution: 1/8000 Exposure time: 40 seconds)
Testing Data
(Gel: 8%SDS-PAGE Lysates (from left to right): Human lung cancer tissue Amount of lysate: 40ug per lane Primary antibody: 1/550 dilution Secondary antibody dilution: 1/8000 Exposure time: 40 seconds)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/40.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/40.)
NCBI and Uniprot Product Information
Uniprot Description
CALCRL: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.
Protein type: Cell cycle regulation; GPCR, family 2; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 2q32.1
Cellular Component: endoplasmic reticulum; integral to plasma membrane; lysosome; plasma membrane; endosome
Molecular Function: G-protein coupled receptor activity; protein binding; calcitonin gene-related polypeptide receptor activity; adrenomedullin receptor activity; protein transporter activity; calcitonin receptor activity
Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; protein transport; regulation of muscle contraction; receptor internalization; heart development; negative regulation of inflammatory response; positive regulation of smooth muscle cell proliferation; calcium ion transport; positive regulation of cAMP biosynthetic process; cAMP biosynthetic process; angiogenesis; G-protein signaling, adenylate cyclase activating pathway
Research Articles on CALCRL
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Product Notes
The CALCRL calcrl (Catalog #AAA9404983) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CALCRL Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CALCRL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500-1:2000 Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the CALCRL calcrl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CALCRL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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