Rabbit anti-Human RPS4X Polyclonal Antibody | anti-RPS4X antibody
RPS4X antibody
NCBI and Uniprot Product Information
NCBI Description
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Uniprot Description
RPS4X: Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Protein type: RNA-binding; Translation; Ribosomal
Chromosomal Location of Human Ortholog: Xq13.1
Cellular Component: polysome; small ribosomal subunit; focal adhesion; membrane; ribosome; ribonucleoprotein complex; cytosol
Molecular Function: rRNA binding; structural constituent of ribosome
Biological Process: SRP-dependent cotranslational protein targeting to membrane; translation; positive regulation of translation; viral reproduction; multicellular organismal development; translational termination; viral infectious cycle; translational elongation; cellular protein metabolic process; positive regulation of cell proliferation; mRNA catabolic process, nonsense-mediated decay; translational initiation; viral transcription; gene expression