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Western Blot (WB) (Western blot analysis of HDGFRP2 in human testis tissue lysate with HDGFRP2 antibody at (A) 0.5 and (B) 1 ug/mL.)

Rabbit HDGFRP2 Polyclonal Antibody | anti-HDGFRP2 antibody

HDGFRP2 Antibody

Gene Names
HDGFRP2; HDGF2; HRP-2; HDGF-2
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
HDGFRP2; Polyclonal Antibody; HDGFRP2 Antibody; Hepatoma-derived growth factor-related protein 2; HDGF2; HRP-2; anti-HDGFRP2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
At least two isoforms of HDGFRP2 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other HDGFRP family members
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
671
Applicable Applications for anti-HDGFRP2 antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against an 18 amino acid peptide near the amino terminus of human HDGFRP2.
Target Name
HDGFRP2
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of HDGFRP2 in human testis tissue lysate with HDGFRP2 antibody at (A) 0.5 and (B) 1 ug/mL.)

Western Blot (WB) (Western blot analysis of HDGFRP2 in human testis tissue lysate with HDGFRP2 antibody at (A) 0.5 and (B) 1 ug/mL.)
Related Product Information for anti-HDGFRP2 antibody
Hepatoma-derived growth factor-related protein 2 (HDGFRP2) is a widely expressed member of protein family that contains the HDGF related proteins 1-4 and lens epithelial derived growth factor (LEDGF). These family members show extensive homology at the amino terminus (termed the hath region). Little is known of the role of HDGFRP2, but like the related LEDGF, HDGFRP2 can bind HIV-1 integrase and stimulate HIV-1 integrase activity in vitro.
Product Categories/Family for anti-HDGFRP2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
74,729 Da
NCBI Official Full Name
hepatoma-derived growth factor-related protein 2, isoform CRA_a
NCBI Official Symbol
HDGFRP2
NCBI Official Synonym Symbols
HDGF2; HRP-2; HDGF-2
NCBI Protein Information
hepatoma-derived growth factor-related protein 2
UniProt Protein Name
Hepatoma-derived growth factor-related protein 2
UniProt Gene Name
HDGFRP2
UniProt Synonym Gene Names
HDGF2; HRP-2; HDGF-2
UniProt Entry Name
HDGR2_HUMAN

NCBI Description

This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. The protein includes an N-terminal PWWP domain that binds to methyl-lysine-containing histones, with specific binding of this protein to tri-methylated lysines 36 and 79 of histone H3, and di- and tri-methylated lysine 20 of histone H4. The protein functions in LEDGF/p75-independent HIV-1 replication by determining HIV-1 integration site selection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Uniprot Description

HDGF2: a member of the hepatoma-derived growth factor (HDGF) family. Two alternatively spliced transcript variants encoding slightly different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; mitochondrion; nucleus

Molecular Function: DNA binding; chromatin binding

Biological Process: transcription, DNA-dependent

Research Articles on HDGFRP2

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Product Notes

The HDGFRP2 hdgfrp2 (Catalog #AAA9403705) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HDGFRP2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HDGFRP2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the HDGFRP2 hdgfrp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HDGFRP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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